Language Processing in Breastfed Infants at Risk of Thiamine Deficiency Benefits From Maternal Thiamine Supplementation

Dare A. Baldwin; Jeffrey Measelle; Lauren Gallivan; Anna Sanchirico; Netanel Weinstein; Anaahat Bala; Kathleen Chan; Jelisa Gallant; Mam Borath; Hou Kroeun; Frank T. Wieringa; Tim J. Green; Kyly C. Whitfield

doi:10.1037/dev0001829

Language Processing in Breastfed Infants at Risk of Thiamine Deficiency Benefits From Maternal Thiamine Supplementation

Dare A. Baldwin, Jeffrey Measelle, Lauren Gallivan, Anna Sanchirico, Netanel Weinstein, Anaahat Bala, Kathleen Chan, Jelisa Gallant, Mam Borath, Hou Kroeun, Frank T. Wieringa, Tim J. Green, Kyly C. Whitfield

Research output: Contribution to journal › Article › peer-review

Abstract

In a double-blind, randomized controlled trial, we investigated relationships between infants’ exposure to thiamine and their language-processing ability. Three hundred thirty-five lactating Cambodian mothers of 161 female/174 male infants received either 0, 1.2, 2.4, or 10 mg of thiamine daily, from 2 to 24 weeks postpartum. We assessed infants’ language processing at 24 weeks via the infant-directed speech (IDS) task, measuring attentional enhancement to IDS versus adult-directed speech. Maternal thiamine supplementation displayed a small but statistically significant dose–response relationship to the magnitude of infants’ IDS-elicited attentional enhancement (adjusted R2 = 0.022, p =.011). As well, only infants whose mothers received a daily thiamine supplement of 10 mg showed fully robust IDS-related attentional enhancement. These findings showcase the IDS Task for monitoring the integrity of infants’ language processing and underscore the importance of adequate thiamine early in life for ensuring optimal language development.

Original language	English
Number of pages	14
Journal	Developmental psychology
DOIs	https://doi.org/10.1037/dev0001829
Publication status	E-pub ahead of print - 19 Dec 2024
Externally published	Yes

Keywords

global mental health
infant-directed speech
language development
Mullen Scales of Early Learning
thiamine supplementation

Access to Document

10.1037/dev0001829Licence: In Copyright

Cite this

Baldwin, D. A., Measelle, J., Gallivan, L., Sanchirico, A., Weinstein, N., Bala, A., Chan, K., Gallant, J., Borath, M., Kroeun, H., Wieringa, F. T., Green, T. J., & Whitfield, K. C. (2024). Language Processing in Breastfed Infants at Risk of Thiamine Deficiency Benefits From Maternal Thiamine Supplementation. Developmental psychology. Advance online publication. https://doi.org/10.1037/dev0001829

@article{78ed9b266cd646928a9f7f335b7362a8,

title = "Language Processing in Breastfed Infants at Risk of Thiamine Deficiency Benefits From Maternal Thiamine Supplementation",

abstract = "In a double-blind, randomized controlled trial, we investigated relationships between infants{\textquoteright} exposure to thiamine and their language-processing ability. Three hundred thirty-five lactating Cambodian mothers of 161 female/174 male infants received either 0, 1.2, 2.4, or 10 mg of thiamine daily, from 2 to 24 weeks postpartum. We assessed infants{\textquoteright} language processing at 24 weeks via the infant-directed speech (IDS) task, measuring attentional enhancement to IDS versus adult-directed speech. Maternal thiamine supplementation displayed a small but statistically significant dose–response relationship to the magnitude of infants{\textquoteright} IDS-elicited attentional enhancement (adjusted R2 = 0.022, p =.011). As well, only infants whose mothers received a daily thiamine supplement of 10 mg showed fully robust IDS-related attentional enhancement. These findings showcase the IDS Task for monitoring the integrity of infants{\textquoteright} language processing and underscore the importance of adequate thiamine early in life for ensuring optimal language development.",

keywords = "global mental health, infant-directed speech, language development, Mullen Scales of Early Learning, thiamine supplementation",

author = "Baldwin, {Dare A.} and Jeffrey Measelle and Lauren Gallivan and Anna Sanchirico and Netanel Weinstein and Anaahat Bala and Kathleen Chan and Jelisa Gallant and Mam Borath and Hou Kroeun and Wieringa, {Frank T.} and Green, {Tim J.} and Whitfield, {Kyly C.}",

year = "2024",

month = dec,

day = "19",

doi = "10.1037/dev0001829",

language = "English",

journal = "Developmental psychology",

issn = "0012-1649",

publisher = "American Psychological Association",

}

TY - JOUR

T1 - Language Processing in Breastfed Infants at Risk of Thiamine Deficiency Benefits From Maternal Thiamine Supplementation

AU - Baldwin, Dare A.

AU - Measelle, Jeffrey

AU - Gallivan, Lauren

AU - Sanchirico, Anna

AU - Weinstein, Netanel

AU - Bala, Anaahat

AU - Chan, Kathleen

AU - Gallant, Jelisa

AU - Borath, Mam

AU - Kroeun, Hou

AU - Wieringa, Frank T.

AU - Green, Tim J.

AU - Whitfield, Kyly C.

PY - 2024/12/19

Y1 - 2024/12/19

N2 - In a double-blind, randomized controlled trial, we investigated relationships between infants’ exposure to thiamine and their language-processing ability. Three hundred thirty-five lactating Cambodian mothers of 161 female/174 male infants received either 0, 1.2, 2.4, or 10 mg of thiamine daily, from 2 to 24 weeks postpartum. We assessed infants’ language processing at 24 weeks via the infant-directed speech (IDS) task, measuring attentional enhancement to IDS versus adult-directed speech. Maternal thiamine supplementation displayed a small but statistically significant dose–response relationship to the magnitude of infants’ IDS-elicited attentional enhancement (adjusted R2 = 0.022, p =.011). As well, only infants whose mothers received a daily thiamine supplement of 10 mg showed fully robust IDS-related attentional enhancement. These findings showcase the IDS Task for monitoring the integrity of infants’ language processing and underscore the importance of adequate thiamine early in life for ensuring optimal language development.

AB - In a double-blind, randomized controlled trial, we investigated relationships between infants’ exposure to thiamine and their language-processing ability. Three hundred thirty-five lactating Cambodian mothers of 161 female/174 male infants received either 0, 1.2, 2.4, or 10 mg of thiamine daily, from 2 to 24 weeks postpartum. We assessed infants’ language processing at 24 weeks via the infant-directed speech (IDS) task, measuring attentional enhancement to IDS versus adult-directed speech. Maternal thiamine supplementation displayed a small but statistically significant dose–response relationship to the magnitude of infants’ IDS-elicited attentional enhancement (adjusted R2 = 0.022, p =.011). As well, only infants whose mothers received a daily thiamine supplement of 10 mg showed fully robust IDS-related attentional enhancement. These findings showcase the IDS Task for monitoring the integrity of infants’ language processing and underscore the importance of adequate thiamine early in life for ensuring optimal language development.

KW - global mental health

KW - infant-directed speech

KW - language development

KW - Mullen Scales of Early Learning

KW - thiamine supplementation

UR - http://www.scopus.com/inward/record.url?scp=85214581901&partnerID=8YFLogxK

U2 - 10.1037/dev0001829

DO - 10.1037/dev0001829

M3 - Article

AN - SCOPUS:85214581901

SN - 0012-1649

JO - Developmental psychology

JF - Developmental psychology

ER -

Language Processing in Breastfed Infants at Risk of Thiamine Deficiency Benefits From Maternal Thiamine Supplementation

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this