1. The cardiovascular response to electrolytic lesions of the A1 noradrenaline cell group (A1 lesion) were studied in the rat. 2. A1 lesions in normal rats cause acute hypertension and bradycardia and elevate plasma arginine‐vasopressin (AVP), as previously described in the rabbit. 3. After A1 lesions in vasopressin deficient rats the hypertension is not reduced compared to that seen in normal rats, but the bradycardia is attenuated. 4. AVP makes a greater contribution to the bradycardia than to the hypertension after A1 lesions.
|Number of pages||4|
|Journal||Clinical and Experimental Pharmacology and Physiology|
|Publication status||Published - Aug 1984|
- A1 noradrenergic neurons
- arterial pressure
- heart rate
- plasma vasopressin