Lesson of the month 2: An unusual cause of depression in an older man: Cushing's syndrome resulting from metastatic small cell cancer of the prostate

Paul Kleinig; Patrick Russell

doi:10.7861/clinmedicine.18-5-432

Lesson of the month 2: An unusual cause of depression in an older man: Cushing's syndrome resulting from metastatic small cell cancer of the prostate

Paul Kleinig
, Patrick Russell

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

This article describes the case of an older patient whose main presenting problem was depression. A constellation of clinical and biochemical features led to a search for medical causes of his low mood, which uncovered ectopic adrenocorticotropic hormone (ACTH) secretion. Post-mortem examination showed that the source of ACTH was small cell neuroendocrine carcinoma of the prostate, and that the patient had died from the sequelae of profound immune suppression.

Original language	English
Pages (from-to)	432-434
Number of pages	3
Journal	Clinical Medicine, Journal of the Royal College of Physicians of London
Volume	18
Issue number	5
DOIs	https://doi.org/10.7861/clinmedicine.18-5-432
Publication status	Published - 1 Oct 2018
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

ACTH syndrome
Autopsy
Carcinoma
Clinicopathological conference
Depression
Ectopic
Prostatic neoplasms
Small cell

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10.7861/clinmedicine.18-5-432Licence: In Copyright

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Lesson of the month 2: An unusual cause of depression in an older man: Cushing's syndrome resulting from metastatic small cell cancer of the prostate. / Kleinig, Paul; Russell, Patrick.
In: Clinical Medicine, Journal of the Royal College of Physicians of London, Vol. 18, No. 5, 01.10.2018, p. 432-434.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

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AU - Kleinig, Paul

AU - Russell, Patrick

PY - 2018/10/1

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AB - This article describes the case of an older patient whose main presenting problem was depression. A constellation of clinical and biochemical features led to a search for medical causes of his low mood, which uncovered ectopic adrenocorticotropic hormone (ACTH) secretion. Post-mortem examination showed that the source of ACTH was small cell neuroendocrine carcinoma of the prostate, and that the patient had died from the sequelae of profound immune suppression.

KW - ACTH syndrome

KW - Autopsy

KW - Carcinoma

KW - Clinicopathological conference

KW - Depression

KW - Ectopic

KW - Prostatic neoplasms

KW - Small cell

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DO - 10.7861/clinmedicine.18-5-432

M3 - Article

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SN - 1470-2118

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JO - Clinical Medicine, Journal of the Royal College of Physicians of London

JF - Clinical Medicine, Journal of the Royal College of Physicians of London

IS - 5

ER -

Lesson of the month 2: An unusual cause of depression in an older man: Cushing's syndrome resulting from metastatic small cell cancer of the prostate

Abstract

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Keywords

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