Liquid and Thin-Layer Chromatography

Simon Lewis, Claire Lenehan

    Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

    3 Citations (Scopus)


    Liquid chromatography is a broad classification used to describe a variety of different chromatographic configurations that rely on the use of a liquid mobile phase. Paper, thin-layer, and classical column chromatography techniques, as well as high-performance liquid chromatography and ion chromatography, all belong to the class of liquid chromatography. A variety of separation mechanisms can be used within liquid chromatography; these include adsorption, ion-exchange, size-exclusion, affinity, and ion-pair formation. A discussion of these separation mechanisms can be found in Chromatography: Basic Principles. This article gives an overview of classical, high-performance, and thin-layer chromatographic techniques including experimental configurations and forensic applications.

    Original languageEnglish
    Title of host publicationEncyclopedia of Forensic Sciences
    Subtitle of host publicationSecond Edition
    PublisherElsevier Inc.
    Number of pages4
    EditionSecond Edition
    ISBN (Electronic)9780123821652
    ISBN (Print)9780123821669
    Publication statusPublished - 21 Feb 2013


    • High-performance liquid chromatography (HPLC)
    • Liquid chromatography
    • Thin-layer chromatography (TLC)


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