Liquid and Thin-Layer Chromatography

S. W. Lewis, C. E. Lenehan

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Liquid chromatography is a broad classification used to describe a variety of different chromatographic configurations that rely on the use of a liquid mobile phase. Paper, thin-layer, and classical column chromatography techniques, as well as high-performance liquid chromatography and ion chromatography, all belong to the class of liquid chromatography. A variety of separation mechanisms can be used within liquid chromatography; these include adsorption, ion-exchange, size-exclusion, affinity, and ion-pair formation. A discussion of these separation mechanisms can be found in Chromatography: Basic Principles. This chapter gives an overview of classical, high-performance, and thin-layer chromatographic techniques including experimental configurations and forensic applications.

Original languageEnglish
Title of host publicationForensic Toxicology
EditorsMax M. Houck
Place of PublicationLondon
PublisherElsevier
Pages61-65
Number of pages5
Edition1st edition
ISBN (Electronic)9780128008188
ISBN (Print)9780128007464
DOIs
Publication statusPublished - 2018

Publication series

NameAdvanced Forensic Science Series
PublisherElsevier

Keywords

  • High-performance liquid chromatography (HPLC)
  • Liquid chromatography
  • Thin-layer chromatography (TLC)

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