Localisation of aryl sulfotransferase expression in human tissues using hybridisation histochemistry and immunohistochemistry

Kelly F. Windmill, Astrid Christiansen, Jacqueline T. Teusner, C. Raman Bhasker, Don J. Birkett, Xiaoyi Zhu, Michael E. McManus

    Research output: Contribution to journalArticlepeer-review

    11 Citations (Scopus)

    Abstract

    To date, the laboratory has cloned seven unique human sulfotransferases; five aryl sulfotransferases (HAST1, HAST2, HAST3, HAST4 and HAST4v), an estrogen sulfotransferase and a dehydroepiandrosterone sulfotransferase. The cellular distribution of human aryl sulfotransferases in human hepatic and extrahepatic tissues has been determined using the techniques of hybridization histochemistry and immunohistochemistry. Human aryl suffotransferase expression was detected in liver, epithelial cells of the gastrointestinal mucosal layer, epithelial cells lining bronchioles and in mammary duct epithelial cells.

    Original languageEnglish
    Pages (from-to)341-346
    Number of pages6
    JournalChemico-Biological Interactions
    Volume109
    Issue number1-3
    DOIs
    Publication statusPublished - 20 Feb 1998

    Keywords

    • Aryl sulfotransferase
    • Human
    • Hybridisation histochemistry
    • Immunohistochemistry

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