Location of positive surgical margins after radical prostatectomy – A systematic review and network meta-analysis

Athul John; Thomas Milton; Aashray Gupta; Brendon Stretton; Joseph Hewitt; Rick Catterwell; Luke Selth; Michael O'Callaghan

doi:10.1111/bju.15743

Location of positive surgical margins after radical prostatectomy – A systematic review and network meta-analysis

Athul John, Thomas Milton, Aashray Gupta, Brendon Stretton, Joseph Hewitt, Rick Catterwell, Luke Selth, Michael O'Callaghan

Research output: Contribution to journal › Meeting Abstract › peer-review

Abstract

Background and Objective: The relevance of positive surgical margins (PSM) in prostate cancer patients undergoing. Radical prostatectomy (RP) remains controversial, given that its prognostic capacity for biochemical recurrence (BCR) and other outcomes is inconsistent. Over the last decade, several studies have explored the location of positive surgical margins and their ability to predict biochemical recurrence. Hence, we aimed to systematically review and perform a network meta-analysis answering the clinical question: Does the location of PSM (Comparator and Intervention) influence the risk of BCR (Outcomes) in men with PSM after RP (Population)?

Original language	English
Pages (from-to)	26-27
Number of pages	2
Journal	BJU International
Volume	129
Issue number	S2
DOIs	https://doi.org/10.1111/bju.15743
Publication status	Published - Jun 2022
Event	74th Urological Society of Australia and New Zealand Annual Scientific Meeting - Gold Coast, Australia Duration: 25 Jun 2022 → 28 Jun 2022

Keywords

Positive surgical margins
Radical prostatectomy
Biochemical recurrence

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title = "Location of positive surgical margins after radical prostatectomy – A systematic review and network meta-analysis",

abstract = "Background and Objective: The relevance of positive surgical margins (PSM) in prostate cancer patients undergoing. Radical prostatectomy (RP) remains controversial, given that its prognostic capacity for biochemical recurrence (BCR) and other outcomes is inconsistent. Over the last decade, several studies have explored the location of positive surgical margins and their ability to predict biochemical recurrence. Hence, we aimed to systematically review and perform a network meta-analysis answering the clinical question: Does the location of PSM (Comparator and Intervention) influence the risk of BCR (Outcomes) in men with PSM after RP (Population)?",

keywords = "Positive surgical margins, Radical prostatectomy, Biochemical recurrence",

author = "Athul John and Thomas Milton and Aashray Gupta and Brendon Stretton and Joseph Hewitt and Rick Catterwell and Luke Selth and Michael O'Callaghan",

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TY - JOUR

T1 - Location of positive surgical margins after radical prostatectomy – A systematic review and network meta-analysis

AU - John, Athul

AU - Milton, Thomas

AU - Gupta, Aashray

AU - Stretton, Brendon

AU - Hewitt, Joseph

AU - Catterwell, Rick

AU - Selth, Luke

AU - O'Callaghan, Michael

PY - 2022/6

Y1 - 2022/6

N2 - Background and Objective: The relevance of positive surgical margins (PSM) in prostate cancer patients undergoing. Radical prostatectomy (RP) remains controversial, given that its prognostic capacity for biochemical recurrence (BCR) and other outcomes is inconsistent. Over the last decade, several studies have explored the location of positive surgical margins and their ability to predict biochemical recurrence. Hence, we aimed to systematically review and perform a network meta-analysis answering the clinical question: Does the location of PSM (Comparator and Intervention) influence the risk of BCR (Outcomes) in men with PSM after RP (Population)?

AB - Background and Objective: The relevance of positive surgical margins (PSM) in prostate cancer patients undergoing. Radical prostatectomy (RP) remains controversial, given that its prognostic capacity for biochemical recurrence (BCR) and other outcomes is inconsistent. Over the last decade, several studies have explored the location of positive surgical margins and their ability to predict biochemical recurrence. Hence, we aimed to systematically review and perform a network meta-analysis answering the clinical question: Does the location of PSM (Comparator and Intervention) influence the risk of BCR (Outcomes) in men with PSM after RP (Population)?

KW - Positive surgical margins

KW - Radical prostatectomy

KW - Biochemical recurrence

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U2 - 10.1111/bju.15743

DO - 10.1111/bju.15743

M3 - Meeting Abstract

SN - 1464-4096

VL - 129

SP - 26

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JO - BJU International

JF - BJU International

IS - S2

T2 - 74th Urological Society of Australia and New Zealand Annual Scientific Meeting

Y2 - 25 June 2022 through 28 June 2022

ER -

Location of positive surgical margins after radical prostatectomy – A systematic review and network meta-analysis

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