Abstract
Purpose: Claudicants are known to have a greater risk of cardiovascular events (CV) due to systemic atherosclerotic burden. Current therapeutic options available for patients with claudication include SET, BMT, or surgical/endovascular revascularisation. This study aimed to determine whether treatment type played a role in the rate of CV events out to 3 yrs in Claudicants.
Methodology: All Claudicants who underwent an exercise ABPI were eligible for inclusion in the study. Claudicants were assigned one of three treatments at the discression of the consulting physician, best medical therapy (BMT), supervised exercise therapy (SET) or surgical/endovascular revascularisation groups. Offering one treatment did not exclude the offering of another treatment at a later time. Claudicants were followed out to 3 yrs and all Cardiovascular and Vascular events were recorded. Data was analysed using Chai-Square analysis.
Results: 201 Claudicants were identified, 78 BMT group, 59 SET group and 64 patients underwent revascularisation. 71% of the revascularisation group were short distance Claudicants compared to 48% in SET and 37% in BMT (p= < 0.05). Within 3yrs, 14% of BMT patients had a CV event, 19% in SET group and 8% in the revascularisation group. (p= > 0.05). Vascular events occurred in 19% of BMT patients, 24% for SET and 51% for revascularisation group (p= > 0.05). Major limb amputations occurred in 1.28% of the BMT group, 3.38% of the SET group and 1.56% in the revascularisation group (p= > 0.05).All cause mortality occurred in 2.56% of the BMT group, 1.72% of the SET group and 14.3% in the revascularisation group (p= < 0.05).
Conclusion: CV events were more frequent in the SET group however this did not reach significance. Vascular events were higher in the revascularisation group but this was not significant and there was no difference in Amputation rate out to three year. All-cause mortality was higher in the Revascularisation group likely due to increased disease severity in this group.
Methodology: All Claudicants who underwent an exercise ABPI were eligible for inclusion in the study. Claudicants were assigned one of three treatments at the discression of the consulting physician, best medical therapy (BMT), supervised exercise therapy (SET) or surgical/endovascular revascularisation groups. Offering one treatment did not exclude the offering of another treatment at a later time. Claudicants were followed out to 3 yrs and all Cardiovascular and Vascular events were recorded. Data was analysed using Chai-Square analysis.
Results: 201 Claudicants were identified, 78 BMT group, 59 SET group and 64 patients underwent revascularisation. 71% of the revascularisation group were short distance Claudicants compared to 48% in SET and 37% in BMT (p= < 0.05). Within 3yrs, 14% of BMT patients had a CV event, 19% in SET group and 8% in the revascularisation group. (p= > 0.05). Vascular events occurred in 19% of BMT patients, 24% for SET and 51% for revascularisation group (p= > 0.05). Major limb amputations occurred in 1.28% of the BMT group, 3.38% of the SET group and 1.56% in the revascularisation group (p= > 0.05).All cause mortality occurred in 2.56% of the BMT group, 1.72% of the SET group and 14.3% in the revascularisation group (p= < 0.05).
Conclusion: CV events were more frequent in the SET group however this did not reach significance. Vascular events were higher in the revascularisation group but this was not significant and there was no difference in Amputation rate out to three year. All-cause mortality was higher in the Revascularisation group likely due to increased disease severity in this group.
| Original language | English |
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| Pages | 79-80 |
| Number of pages | 2 |
| Publication status | Published - 2016 |
| Event | Australian and New Zealand Society for Vascular Surgery Annual Scientific Meeting, 2016: Vascular Challenges - Sheraton on The Park, Sydney, Australia Duration: 5 Aug 2016 → 8 Aug 2016 https://www.anzsvs.org.au/wp-content/uploads/2018/11/LTR-2016-05-10-Newsletter-May-2016.pdf (Newsletter description of upcoming conference) |
Conference
| Conference | Australian and New Zealand Society for Vascular Surgery Annual Scientific Meeting, 2016 |
|---|---|
| Abbreviated title | ANZSVS 2016 |
| Country/Territory | Australia |
| City | Sydney |
| Period | 5/08/16 → 8/08/16 |
| Other | ANZSVS 2016 – Sydney The ANZSVS meeting will be returning to Sydney in 2016, Friday 5 August to Monday 8 August at Sheraton on The Park. The theme is "Vascular Challenges" where we will be exploring controversies relevant to surgeons practicing open vascular surgery and performing endovascular interventions in Australia and New Zealand. The Vascular Nurses will again join us in a parallel ANZSVN stream and there will be a Vascular Imaging Symposium Friday 5th August. Confirmed invited speakers include Andrew Holden (New Zealand), Armando Lobato (Brazil), Michel Reijnen (The Netherlands), Marc Schermerhorn (Boston, USA), Guido Rohani (Frankfurt, Germany) and Matthew Smeds (USA). We look forward to seeing you there. A. Freeman |
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Keywords
- Claudicants
- Cardiovascular events