Low Relative Abundances of the Mucolytic Bacterium Akkermansia muciniphila and Bifidobacterium spp. in Feces of Children with Autism

L Wang, Claus Christophersen, Michael Sorich, Jacobus Gerber, Manya Angley, Michael Conlon

    Research output: Contribution to journalArticlepeer-review

    206 Citations (Scopus)

    Abstract

    Gastrointestinal disturbance is frequently reported for individuals with autism. We used quantitative real-time PCR analysis to quantify fecal bacteria that could influence gastrointestinal health in children with and without autism. Lower relative abundances of Bifidobacteria species and the mucolytic bacterium Akkermansia muciniphila were found in children with autism, the latter suggesting mucus barrier changes.

    Original languageEnglish
    Pages (from-to)6718-6721
    Number of pages4
    JournalApplied and Environmental Microbiology
    Volume77
    Issue number18
    DOIs
    Publication statusPublished - Sep 2011

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