Low Relative Abundances of the Mucolytic Bacterium Akkermansia muciniphila and Bifidobacterium spp. in Feces of Children with Autism

L Wang; Claus Christophersen; Michael Sorich; Jacobus Gerber; Manya Angley; Michael Conlon

doi:10.1128/AEM.05212-11

Low Relative Abundances of the Mucolytic Bacterium Akkermansia muciniphila and Bifidobacterium spp. in Feces of Children with Autism

L Wang, Claus Christophersen, Michael Sorich, Jacobus Gerber, Manya Angley, Michael Conlon

Research output: Contribution to journal › Article › peer-review

356 Citations (Scopus)

Abstract

Gastrointestinal disturbance is frequently reported for individuals with autism. We used quantitative real-time PCR analysis to quantify fecal bacteria that could influence gastrointestinal health in children with and without autism. Lower relative abundances of Bifidobacteria species and the mucolytic bacterium Akkermansia muciniphila were found in children with autism, the latter suggesting mucus barrier changes.

Original language	English
Pages (from-to)	6718-6721
Number of pages	4
Journal	Applied and Environmental Microbiology
Volume	77
Issue number	18
DOIs	https://doi.org/10.1128/AEM.05212-11
Publication status	Published - Sept 2011

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title = "Low Relative Abundances of the Mucolytic Bacterium Akkermansia muciniphila and Bifidobacterium spp. in Feces of Children with Autism",

abstract = "Gastrointestinal disturbance is frequently reported for individuals with autism. We used quantitative real-time PCR analysis to quantify fecal bacteria that could influence gastrointestinal health in children with and without autism. Lower relative abundances of Bifidobacteria species and the mucolytic bacterium Akkermansia muciniphila were found in children with autism, the latter suggesting mucus barrier changes.",

author = "L Wang and Claus Christophersen and Michael Sorich and Jacobus Gerber and Manya Angley and Michael Conlon",

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AU - Sorich, Michael

AU - Gerber, Jacobus

AU - Angley, Manya

AU - Conlon, Michael

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AB - Gastrointestinal disturbance is frequently reported for individuals with autism. We used quantitative real-time PCR analysis to quantify fecal bacteria that could influence gastrointestinal health in children with and without autism. Lower relative abundances of Bifidobacteria species and the mucolytic bacterium Akkermansia muciniphila were found in children with autism, the latter suggesting mucus barrier changes.

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JO - Applied and Environmental Microbiology

JF - Applied and Environmental Microbiology

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ER -

Low Relative Abundances of the Mucolytic Bacterium Akkermansia muciniphila and Bifidobacterium spp. in Feces of Children with Autism

Abstract

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