Lymph node yield following colorectal cancer surgery.

Kathryn Field, C Platell, N Rieger, Iain Skinner, David Wattchow, Ian Jones, Frank Chen, Suzanne Kosmider, Tony Wohlers, Marienne Hibbert, Peter Gibbs

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    6 Citations (Scopus)

    Abstract

    Background: Lymph node yield (LNY) is a measure of quality of care and a strong prognostic factor for outcome from colorectal cancer (CRC). The main aims of this study were to determine LNY across multiple Australian centres and the clinico-pathologic factors that influence yield. Methods: Analysis of data from prospective CRC databases at 11 Australian centres between January 1988 and May 2008 was undertaken utilizing the linkage and analysis resources of BioGrid Australia. The LNY depending on different clinico-pathologic patient characteristics was evaluated. Results: In total, 10082 cases (54.1% men, 45.9% women) were identified. Median LNY was 12 (range 0-174). LNY increased significantly (P < 0.001) over time, from a mean of 8.5 in 1988 to 13 in 2008. LNY also varied significantly between surgical centres. Female gender, younger age, right-sided disease, higher T and N stage, specific operation types and absence of preoperative radiotherapy were all significantly associated with higher LNY. Conclusions: While varying across centres, the median LNYs in Australia are acceptable and have improved significantly over recent years. Multiple clinico-pathologic factors significantly influence the number of nodes retrieved.

    Original languageEnglish
    Pages (from-to)266-271
    Number of pages6
    JournalANZ Journal of Surgery
    Volume81
    Issue number4
    DOIs
    Publication statusPublished - 2011

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    Field, K., Platell, C., Rieger, N., Skinner, I., Wattchow, D., Jones, I., Chen, F., Kosmider, S., Wohlers, T., Hibbert, M., & Gibbs, P. (2011). Lymph node yield following colorectal cancer surgery. ANZ Journal of Surgery, 81(4), 266-271. https://doi.org/10.1111/j.1445-2197.2010.05571.x