TY - JOUR
T1 - Magnesium and Human Health
T2 - Perspectives and Research Directions
AU - Al Alawi, Abdullah M.
AU - Majoni, Sandawana William
AU - Falhammar, Henrik
PY - 2018/5/16
Y1 - 2018/5/16
N2 - Magnesium is the fourth most abundant cation in the body. It has several functions in the human body including its role as a cofactor for more than 300 enzymatic reactions. Several studies have shown that hypomagnesemia is a common electrolyte derangement in clinical setting especially in patients admitted to intensive care unit where it has been found to be associated with increase mortality and hospital stay. Hypomagnesemia can be caused by a wide range of inherited and acquired diseases. It can also be a side effect of several medications. Many studies have reported that reduced levels of magnesium are associated with a wide range of chronic diseases. Magnesium can play important therapeutic and preventive role in several conditions such as diabetes, osteoporosis, bronchial asthma, preeclampsia, migraine, and cardiovascular diseases. This review is aimed at comprehensively collating the current available published evidence and clinical correlates of magnesium disorders.
AB - Magnesium is the fourth most abundant cation in the body. It has several functions in the human body including its role as a cofactor for more than 300 enzymatic reactions. Several studies have shown that hypomagnesemia is a common electrolyte derangement in clinical setting especially in patients admitted to intensive care unit where it has been found to be associated with increase mortality and hospital stay. Hypomagnesemia can be caused by a wide range of inherited and acquired diseases. It can also be a side effect of several medications. Many studies have reported that reduced levels of magnesium are associated with a wide range of chronic diseases. Magnesium can play important therapeutic and preventive role in several conditions such as diabetes, osteoporosis, bronchial asthma, preeclampsia, migraine, and cardiovascular diseases. This review is aimed at comprehensively collating the current available published evidence and clinical correlates of magnesium disorders.
KW - magnesium disorders
KW - hypomagnesemia
KW - magnesium homeostasis
UR - http://www.scopus.com/inward/record.url?scp=85057971385&partnerID=8YFLogxK
U2 - 10.1155/2018/9041694
DO - 10.1155/2018/9041694
M3 - Review article
AN - SCOPUS:85057971385
SN - 1687-8337
VL - 2018
JO - International Journal of Endocrinology
JF - International Journal of Endocrinology
M1 - 9041694
ER -
