Maintenance of ancestral complexity and non-metazoan genes in two basal cnidarians

Ulrich Technau; Stephen A. Rudd; Peter Maxwell; Paul M.K. Gordon; Michael Saina; Lauretta C. Grasso; David C. Hayward; Christoph W. Sensen; Robert B. Saint; Thomas W. Holstein; Eldon E. Ball; David John Miller

doi:10.1016/j.tig.2005.09.007

Maintenance of ancestral complexity and non-metazoan genes in two basal cnidarians

Ulrich Technau, Stephen A. Rudd, Peter Maxwell, Paul M.K. Gordon, Michael Saina, Lauretta C. Grasso, David C. Hayward, Christoph W. Sensen, Robert B. Saint, Thomas W. Holstein, Eldon E. Ball, David John Miller

Deputy Vice-Chancellor (Research)

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267 Citations (Scopus)

Abstract

Cnidarians are among the simplest extant animals; however EST analyses reveal that they have a remarkably high level of genetic complexity. In this article, we show that the full diversity of metazoan signaling pathways is represented in this phylum, as are antagonists previously known only in chordates. Many of the cnidarian ESTs match genes previously known only in non-animal kingdoms. At least some of these represent ancient genes lost by all bilaterians examined so far, rather than genes gained by recent lateral gene transfer.

Original language	English
Pages (from-to)	633-639
Number of pages	7
Journal	Trends in Genetics
Volume	21
Issue number	12
DOIs	https://doi.org/10.1016/j.tig.2005.09.007
Publication status	Published - Dec 2005

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title = "Maintenance of ancestral complexity and non-metazoan genes in two basal cnidarians",

abstract = "Cnidarians are among the simplest extant animals; however EST analyses reveal that they have a remarkably high level of genetic complexity. In this article, we show that the full diversity of metazoan signaling pathways is represented in this phylum, as are antagonists previously known only in chordates. Many of the cnidarian ESTs match genes previously known only in non-animal kingdoms. At least some of these represent ancient genes lost by all bilaterians examined so far, rather than genes gained by recent lateral gene transfer.",

author = "Ulrich Technau and Rudd, {Stephen A.} and Peter Maxwell and Gordon, {Paul M.K.} and Michael Saina and Grasso, {Lauretta C.} and Hayward, {David C.} and Sensen, {Christoph W.} and Saint, {Robert B.} and Holstein, {Thomas W.} and Ball, {Eldon E.} and Miller, {David John}",

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language = "English",

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T1 - Maintenance of ancestral complexity and non-metazoan genes in two basal cnidarians

AU - Technau, Ulrich

AU - Rudd, Stephen A.

AU - Maxwell, Peter

AU - Gordon, Paul M.K.

AU - Saina, Michael

AU - Grasso, Lauretta C.

AU - Hayward, David C.

AU - Sensen, Christoph W.

AU - Saint, Robert B.

AU - Holstein, Thomas W.

AU - Ball, Eldon E.

AU - Miller, David John

PY - 2005/12

Y1 - 2005/12

N2 - Cnidarians are among the simplest extant animals; however EST analyses reveal that they have a remarkably high level of genetic complexity. In this article, we show that the full diversity of metazoan signaling pathways is represented in this phylum, as are antagonists previously known only in chordates. Many of the cnidarian ESTs match genes previously known only in non-animal kingdoms. At least some of these represent ancient genes lost by all bilaterians examined so far, rather than genes gained by recent lateral gene transfer.

AB - Cnidarians are among the simplest extant animals; however EST analyses reveal that they have a remarkably high level of genetic complexity. In this article, we show that the full diversity of metazoan signaling pathways is represented in this phylum, as are antagonists previously known only in chordates. Many of the cnidarian ESTs match genes previously known only in non-animal kingdoms. At least some of these represent ancient genes lost by all bilaterians examined so far, rather than genes gained by recent lateral gene transfer.

U2 - 10.1016/j.tig.2005.09.007

DO - 10.1016/j.tig.2005.09.007

M3 - Article

SN - 0168-9525

VL - 21

SP - 633

EP - 639

JO - Trends in Genetics

JF - Trends in Genetics

IS - 12

ER -

Maintenance of ancestral complexity and non-metazoan genes in two basal cnidarians

Abstract

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