Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


    Esophageal manometry has been in use for physiological measurement and diagnostics for many years. Solid-state high-resolution manometry (HRM) offers the ability to record pressures from the upper esophageal sphincter to the stomach with fidelity and high spatial resolution, and this has led to the definition of new objective biomechanical measures that may guide clinical decisionmaking in relation to paediatric patients with typical gastroesophageal reflux (GER) disease symptoms. The most important application of HRM is for the preoperative investigation of children undergoing work-up for anti-reflux surgery. Whilst the performance of HRM can be challenging in younger children, HRM can be used to exclude achalasia as a cause of typical symptoms and can provide a range of information on esophageal biomechanics that may be informative for determining disease severity. This includes characterisation of esophageal peristalsis and esophagogastric junction (EGJ) barrier function, based upon EGJ hiatus hernia subtype morphology and EGJ contractility. HRM may potentially have a role for investigation of recurrent transit hold-up symptoms following anti-reflux surgery. Finally, HRM may differentiate GER disease from rumination syndrome.

    Original languageEnglish
    Title of host publicationGastroesophageal Reflux in Children
    EditorsYvan Vandenplas
    Place of PublicationSwitzerland
    Number of pages13
    ISBN (Electronic)9783319606781
    ISBN (Print)9783319606774
    Publication statusPublished - 28 Sept 2017


    • Diagnosis
    • Dysphagia
    • Esophageal motility
    • Gastroesophageal reflux
    • High-resolution manometry


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