Marine actinomycetes-derived natural products

Chengfang Yang; Rui Qian; Yao Xu; Junxi Yi; Yiwen Gu; Xiaoyu Liu; Haobing Yu; Binghua Jiao; Xiaoling Lu; Wei Zhang

doi:10.2174/1568026619666191114102359

Marine actinomycetes-derived natural products

Chengfang Yang, Rui Qian, Yao Xu, Junxi Yi, Yiwen Gu, Xiaoyu Liu, Haobing Yu, Binghua Jiao, Xiaoling Lu, Wei Zhang

Research output: Contribution to journal › Review article › peer-review

4 Citations (Scopus)

Abstract

Actinomycetes is an abundant resource for discovering a large number of lead compounds, which play an important role in microbial drug discovery. Compared to terrestrial microorganisms, marine actinomycetes have unique metabolic pathways because of their special living environment, which has the potential to produce a variety of bioactive substances. In this paper, secondary metabolites isolated from marine actinomycetes are reviewed (2013-2018), most of which exhibited cytotoxic, antibacterial, and antiviral biological activities.

Original language	English
Pages (from-to)	2868-2918
Number of pages	51
Journal	CURRENT TOPICS IN MEDICINAL CHEMISTRY
Volume	19
Issue number	31
DOIs	https://doi.org/10.2174/1568026619666191114102359
Publication status	Published - 1 Jan 2019

Keywords

Antibacterial activity
Antiviral activity
Cytotoxic activity
Lead compound
Marine actinomycetes
Secondary metabolites

Access to Document

10.2174/1568026619666191114102359Licence: In Copyright

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Cite this

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title = "Marine actinomycetes-derived natural products",

abstract = "Actinomycetes is an abundant resource for discovering a large number of lead compounds, which play an important role in microbial drug discovery. Compared to terrestrial microorganisms, marine actinomycetes have unique metabolic pathways because of their special living environment, which has the potential to produce a variety of bioactive substances. In this paper, secondary metabolites isolated from marine actinomycetes are reviewed (2013-2018), most of which exhibited cytotoxic, antibacterial, and antiviral biological activities.",

keywords = "Antibacterial activity, Antiviral activity, Cytotoxic activity, Lead compound, Marine actinomycetes, Secondary metabolites",

author = "Chengfang Yang and Rui Qian and Yao Xu and Junxi Yi and Yiwen Gu and Xiaoyu Liu and Haobing Yu and Binghua Jiao and Xiaoling Lu and Wei Zhang",

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TY - JOUR

T1 - Marine actinomycetes-derived natural products

AU - Yang, Chengfang

AU - Qian, Rui

AU - Xu, Yao

AU - Yi, Junxi

AU - Gu, Yiwen

AU - Liu, Xiaoyu

AU - Yu, Haobing

AU - Jiao, Binghua

AU - Lu, Xiaoling

AU - Zhang, Wei

PY - 2019/1/1

Y1 - 2019/1/1

N2 - Actinomycetes is an abundant resource for discovering a large number of lead compounds, which play an important role in microbial drug discovery. Compared to terrestrial microorganisms, marine actinomycetes have unique metabolic pathways because of their special living environment, which has the potential to produce a variety of bioactive substances. In this paper, secondary metabolites isolated from marine actinomycetes are reviewed (2013-2018), most of which exhibited cytotoxic, antibacterial, and antiviral biological activities.

AB - Actinomycetes is an abundant resource for discovering a large number of lead compounds, which play an important role in microbial drug discovery. Compared to terrestrial microorganisms, marine actinomycetes have unique metabolic pathways because of their special living environment, which has the potential to produce a variety of bioactive substances. In this paper, secondary metabolites isolated from marine actinomycetes are reviewed (2013-2018), most of which exhibited cytotoxic, antibacterial, and antiviral biological activities.

KW - Antibacterial activity

KW - Antiviral activity

KW - Cytotoxic activity

KW - Lead compound

KW - Marine actinomycetes

KW - Secondary metabolites

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U2 - 10.2174/1568026619666191114102359

DO - 10.2174/1568026619666191114102359

M3 - Review article

C2 - 31724505

AN - SCOPUS:85077761562

VL - 19

SP - 2868

EP - 2918

JO - CURRENT TOPICS IN MEDICINAL CHEMISTRY

JF - CURRENT TOPICS IN MEDICINAL CHEMISTRY

SN - 1568-0266

IS - 31

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