Marine actinomycetes-derived natural products

Chengfang Yang, Rui Qian, Yao Xu, Junxi Yi, Yiwen Gu, Xiaoyu Liu, Haobing Yu, Binghua Jiao, Xiaoling Lu, Wei Zhang

    Research output: Contribution to journalReview articlepeer-review

    6 Citations (Scopus)

    Abstract

    Actinomycetes is an abundant resource for discovering a large number of lead compounds, which play an important role in microbial drug discovery. Compared to terrestrial microorganisms, marine actinomycetes have unique metabolic pathways because of their special living environment, which has the potential to produce a variety of bioactive substances. In this paper, secondary metabolites isolated from marine actinomycetes are reviewed (2013-2018), most of which exhibited cytotoxic, antibacterial, and antiviral biological activities.

    Original languageEnglish
    Pages (from-to)2868-2918
    Number of pages51
    JournalCURRENT TOPICS IN MEDICINAL CHEMISTRY
    Volume19
    Issue number31
    DOIs
    Publication statusPublished - 1 Jan 2019

    Keywords

    • Antibacterial activity
    • Antiviral activity
    • Cytotoxic activity
    • Lead compound
    • Marine actinomycetes
    • Secondary metabolites

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