Marine Sponge Derived Natural Products between 2001 and 2010: Trends and Opportunities for Discovery of Bioactives.

Mohammad Mehbub, Jie Lei, Christopher Franco, Wei Zhang

    Research output: Contribution to journalReview articlepeer-review

    210 Citations (Scopus)

    Abstract

    Marine sponges belonging to the phylum Porifera (Metazoa), evolutionarily the oldest animals are the single best source of marine natural products. The present review presents a comprehensive overview of the source, taxonomy, country of origin or geographical position, chemical class, and biological activity of sponge-derived new natural products discovered between 2001 and 2010. The data has been analyzed with a view to gaining an outlook on the future trends and opportunities in the search for new compounds and their sources from marine sponges.

    Original languageEnglish
    Pages (from-to)4539-4577
    Number of pages39
    JournalMarine Drugs
    Volume12
    Issue number8
    DOIs
    Publication statusPublished - 1 Aug 2014

    Keywords

    • Anticancer
    • Bioactive compounds
    • Drug
    • Marine natural products
    • Marine sponges
    • Porifera
    • Sponge-associated bacteria

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