Marine viruses discovered via metagenomics shed light on viral strategies throughout the oceans

Felipe H. Coutinho, Cynthia B. Silveira, Gustavo B. Gregoracci, Cristiane C. Thompson, Robert A. Edwards, Corina P.D. Brussaard, Bas E. Dutilh, Fabiano L. Thompson

Research output: Contribution to journalArticle

60 Citations (Scopus)

Abstract

Marine viruses are key drivers of host diversity, population dynamics and biogeochemical cycling and contribute to the daily flux of billions of tons of organic matter. Despite recent advancements in metagenomics, much of their biodiversity remains uncharacterized. Here we report a data set of 27,346 marine virome contigs that includes 44 complete genomes. These outnumber all currently known phage genomes in marine habitats and include members of previously uncharacterized lineages. We designed a new method for host prediction based on co-occurrence associations that reveals these viruses infect dominant members of the marine microbiome such as Prochlorococcus and Pelagibacter. A negative association between host abundance and the virus-to-host ratio supports the recently proposed Piggyback-the-Winner model of reduced phage lysis at higher host densities. An analysis of the abundance patterns of viruses throughout the oceans revealed how marine viral communities adapt to various seasonal, temperature and photic regimes according to targeted hosts and the diversity of auxiliary metabolic genes.

Original languageEnglish
Article number15955
Number of pages12
JournalNature Communications
Volume8
DOIs
Publication statusPublished - 5 Jul 2017
Externally publishedYes

Bibliographical note

This article is licensed under a Creative CommonsAttribution 4.0 International License, which permits use, sharing,adaptation, distribution and reproduction in any medium or format, as long as you giveappropriate credit to the original author(s) and the source, provide a link to the CreativeCommons license, and indicate if changes were made. The images or other third partymaterial in this article are included in the article’s Creative Commons license, unlessindicated otherwise in a credit line to the material. If material is not included in thearticle’s Creative Commons license and your intended use is not permitted by statutoryregulation or exceeds the permitted use, you will need to obtain permission directly fromthe copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

Keywords

  • Marine biology
  • Metagenomics
  • Microbial ecology
  • Water microbiology

Fingerprint Dive into the research topics of 'Marine viruses discovered via metagenomics shed light on viral strategies throughout the oceans'. Together they form a unique fingerprint.

  • Cite this

    Coutinho, F. H., Silveira, C. B., Gregoracci, G. B., Thompson, C. C., Edwards, R. A., Brussaard, C. P. D., Dutilh, B. E., & Thompson, F. L. (2017). Marine viruses discovered via metagenomics shed light on viral strategies throughout the oceans. Nature Communications, 8, [15955]. https://doi.org/10.1038/ncomms15955