Maternal and neonatal outcomes following induction of labor: a cohort study

Rosalie Grivell, Aimee Reilly, Helena Oakey, Annabelle Chan, Jodie Dodd

    Research output: Contribution to journalArticlepeer-review

    40 Citations (Scopus)


    Objective. To evaluate maternal and neonatal outcomes associated with birth at term by week of gestational age and also by onset of labor. Design. Cohort study. Setting. A state-wide perinatal outcome database. Population. 28 626 women with spontaneous onset of labor, induction of labor for recognized indications and induction of labor for non-recognized indications. Methods. Cohort study utilizing a validated dataset comparing outcomes with type of onset of labor using a log binomial model. Main outcome measures. Cesarean section, assisted vaginal birth, important measures of maternal and neonatal morbidity. Results. Induction of labor for non-recognized indications was associated with a significantly increased risk of a range of outcomes, including cesarean section (RR 1.67, 95%CI 1.55-1.80). The lowest risk of adverse maternal and infant outcome occurred with birth between 38 and 39 weeks and with the spontaneous onset of labor. Conclusions. Induction of labor for non-recognized indications at term is associated with an increased risk of adverse outcomes. Caution is warranted with a liberal policy of induction of labor at term in an otherwise uncomplicated pregnancy.

    Original languageEnglish
    Pages (from-to)198-203
    Number of pages6
    JournalActa Obstetricia et Gynecologica Scandinavica
    Issue number2
    Publication statusPublished - Feb 2012


    • Induction
    • labor
    • maternal
    • morbidity
    • neonatal


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