Human serum dopamine β hydroxylase [3,4 dihydroxyphenylethylamine, ascorbate: oxygen oxidoreductase (β hydroxylating), EC 18.104.22.168] levels were determined in 52 examples with a newly devised radioimmunoassay that utilizes purified human enzyme and its specific antiserum. The values obtained were in excellent agreement (correlation coefficient r= 0.98) with those obtained by measuring enzymatic activity in the same sera. Either assay technique, enzymatic or homologous radioimmunoassay, can be used for measurement of the enzyme in normal human serum.
|Number of pages||3|
|Journal||Proceedings of the National Academy of Sciences of the United States of America|
|Publication status||Published - Feb 1975|