Abstract
The use of imine compounds to generate alkyl radicals has been a topic of interest among synthetic chemists. However, the mechanism behind this conversion has yet to be fully understood. To shed light on this, a recent study utilized density functional theory calculations to investigate the mechanisms of photocatalyzed imidoyl radical formation and conversion. The study found that a sequential energy transfer, single electron transfer, and proton transfer pathway was energetically favorable for imidoyl radical generation. Interestingly, another substrate lacking 2,4,6-trimethoxy substituents exhibited poor reactivity due to its weak reduction ability and acidity, both in the ground state and photo-excited state.
Original language | English |
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Pages (from-to) | 4565-4572 |
Number of pages | 8 |
Journal | Organic Chemistry Frontiers |
Volume | 10 |
Issue number | 18 |
Early online date | 28 Jul 2023 |
DOIs | |
Publication status | Published - 28 Jul 2023 |
Keywords
- Imines
- alkyl radicals
- photocatalyzed imidoyl radicals