Medicine-related problems: A recurrent issue among residents living in nursing homes

Gereltuya Dorj, Renly Lim, Lisa Kalisch Ellett, Thu Lan Kelly, Andre Andrade, Imaina Widagdo, Nicole Pratt, Rebecca Bilton, Elizabeth Roughead

Research output: Contribution to journalArticlepeer-review

3 Downloads (Pure)


Aim: To examine the incidence and nature of medicine-related problems over time experienced by nursing home residents.

Method: We analyzed records collected in the Reducing Medicine-Induced Deterioration and Adverse Events (ReMInDAR) trial. The trial pharmacists provided services to reduce medicine-induced deterioration and adverse reactions for residents every 8-weeks over a year. The problems identified by the pharmacists were documented in reports and subsequently classified independently by research pharmacists using the D.O.C.U.M.E.N.T system. The number and type of problems at each service and time to develop a new problem post first session were assessed. All analyses were performed using R software (Version 4.1.1). 

Results: The cohort was 115 nursing home residents who received 575 services. In the 12-months, a total of 673 medicine-related problems or symptom reports were identified in 112 residents. Most residents (75%) experienced a new medicine-related problem by the fourth month post the first assessment. After the first session, the proportion of residents with a new medicine-related problem or symptom report declined at each repeated pharmacy session (59% at visit 2 vs. 28% at visit 6, p < 0.01).

Conclusion: Residents living in nursing homes frequently experience medicine-related problems. Our results suggest clinical pharmacist services performed every 4-months may have the potential to reduce the medicine-related problems in nursing homes.

Original languageEnglish
Article number978871
Number of pages9
JournalFrontiers in Pharmacology
Publication statusPublished - 29 Aug 2022
Externally publishedYes


  • adverse effects
  • inappropriate prescribing
  • long-term care
  • medication reconciliation
  • medication therapy management
  • medicine-related problems
  • pharmacy services
  • prescription drug misuse


Dive into the research topics of 'Medicine-related problems: A recurrent issue among residents living in nursing homes'. Together they form a unique fingerprint.

Cite this