Melanopsin knock-out mice have abnormal refractive development and increased susceptibility to form-deprivation myopia

Ranjay Chakraborty, Duk Cheon Lee, Erica G. Landis, Michael A. Bergen, Hanna Park, Curran Sidhu, Samar Hattar, P. Michael Iuvone, Richard A. Stone, Machelle T. Pardue

Research output: Contribution to conferenceAbstractpeer-review

Abstract

Melanopsin, a photopigment in intrinsically photosensitive retinal ganglion cells (ipRGCs), is involved in regulating visual signaling, retinal dopaminergic cell activity, and circadian activity. Here, we examined the contribution of melanopsin to normal refractive development and to visual form-deprivation (FD) in a mutant mouse lacking melanopsin (Opn4-/-).
Original languageEnglish
Number of pages2
Publication statusPublished - May 2015
Externally publishedYes
EventThe Association for Research in Vision and Ophthalmology annual meeting 2012 - Fort Lauderdale Convention Center, Fort Lauderdale, United States
Duration: 6 May 201210 May 2012
Conference number: 14

Conference

ConferenceThe Association for Research in Vision and Ophthalmology annual meeting 2012
Abbreviated titleARVO 2012
CountryUnited States
CityFort Lauderdale
Period6/05/1210/05/12

Keywords

  • Melanopsin
  • abnormal refractive development
  • mice

Fingerprint Dive into the research topics of 'Melanopsin knock-out mice have abnormal refractive development and increased susceptibility to form-deprivation myopia'. Together they form a unique fingerprint.

Cite this