TY - JOUR
T1 - Melioidosis and end-stage renal disease in tropical northern Australia
AU - Chalmers, Rachel M.S.
AU - Majoni, Sandawana W.
AU - Ward, Linda
AU - Perry, Greg J.
AU - Jabbar, Zulfikar
AU - Currie, Bart J.
PY - 2014/11/5
Y1 - 2014/11/5
N2 - Melioidosis, an infection caused by the Gram-negative bacillus Burkholderia pseudomallei, is endemic in Southeast Asia and northern Australia.1 Presentations include disseminated sepsis with multiorgan abscesses, pneumonia, genitourinary infection, skin and soft tissue infection, osteomyelitis/septic arthritis, and neurological melioidosis. It can be acute or chronic and localized or systemic. Pneumonia is the most common presentation.2 It is the commonest cause of severe community-acquired pneumonia in the tropical Top End of northern Australia during the monsoonal wet season.3 Therapy requires at least 2 weeks of intravenous antibiotics followed by at least 3 months of oral therapy to eradicate infection.
AB - Melioidosis, an infection caused by the Gram-negative bacillus Burkholderia pseudomallei, is endemic in Southeast Asia and northern Australia.1 Presentations include disseminated sepsis with multiorgan abscesses, pneumonia, genitourinary infection, skin and soft tissue infection, osteomyelitis/septic arthritis, and neurological melioidosis. It can be acute or chronic and localized or systemic. Pneumonia is the most common presentation.2 It is the commonest cause of severe community-acquired pneumonia in the tropical Top End of northern Australia during the monsoonal wet season.3 Therapy requires at least 2 weeks of intravenous antibiotics followed by at least 3 months of oral therapy to eradicate infection.
UR - http://www.scopus.com/inward/record.url?scp=84908507625&partnerID=8YFLogxK
U2 - 10.1038/ki.2014.228
DO - 10.1038/ki.2014.228
M3 - Article
C2 - 25360487
AN - SCOPUS:84908507625
VL - 86
SP - 867
EP - 870
JO - Kidney International
JF - Kidney International
SN - 0085-2538
IS - 5
ER -