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Metastatic colorectal cancer- third line therapy and beyond

Research output: Contribution to journalReview articlepeer-review

1 Citation (Scopus)

Abstract

Introduction: The outcome of patients with metastatic colorectal cancer (mCRC) has improved significantly in the last few decades. Metastatic colorectal cancer is a highly heterogenous cancer. Beyond second line chemotherapy, treatment decisions are often based on molecular testing. 

Method: In this narrative review, we provide a comprehensive summary of data from key clinical trials and discuss how to integrate these agents into the current treatment landscape of metastatic colorectal cancer. 

Expert Opinion: In the era of precision medicine, molecular testing plays an increasingly important role in the management of mCRC. Efforts need to be made to target treatment based on molecular test results.

Original languageEnglish
Pages (from-to)219-227
Number of pages9
JournalExpert Review of Anticancer Therapy
Volume24
Issue number5
Early online date3 Apr 2024
DOIs
Publication statusPublished - May 2024

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • biomarkers
  • immunotherapy
  • Metastatic colorectal cancer
  • refractory disease
  • targeted therapy

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