Methods for study of mutations and mutagenesis in human lymphocytes

A. A. Morley, K. J. Trainor, J. L. Dempsey, R. S. Seshadri

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    51 Citations (Scopus)


    Detailed methods are presented for measurement and study of in vivo mutations and in vitro mutagenesis in human lymphocytes. The methods described include preparation of conditioned medium containing inteleukin-2, enumeration of mutant clones, in vitro mutagenesis, and expansion of mutant clones for further study.

    Original languageEnglish
    Pages (from-to)363-367
    Number of pages5
    JournalMutation Research/Environmental Mutagenesis and Related Subjects
    Issue number6
    Publication statusPublished - Dec 1985


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