Mindfulness training does not reduce inflammatory cytokine levels in chronic tension-type headache

Stuart Cathcart, Chris Della Vedova, Maarten Immink, Michael Proeve, John Hayball

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

To examine effects of mindfulness training on serum proinflammatory cytokine levels in chronic tension-type headache (CTH) sufferers. Method: Forty-three CTH sufferers participated in a randomized wait-list controlled trial of a mindfulness intervention for headache. Serum concentrations of cytokines IL1-β, IL-2, IL-6, IL-8, IL-12, IL-18, IFN-γ, MCP-1 and TNF-α were measured before and after treatment/wait-list control conditions. Results: Repeated Measures Analysis of Variance revealed that IL1- β, IL-6, IL-8, MCP-1 and TNF-α decreased from pre to post assessments in the treatment and wait-list groups, with no group or group x time effects. Conclusions: Mindfulness training compared to a wait-list control condition does not reduce serum cytokine levels in CTH sufferers.

Original languageEnglish
Pages (from-to)235-238
Number of pages4
JournalJournal of Pain Management
Volume6
Issue number3
Publication statusPublished - 2013
Externally publishedYes

Keywords

  • Cytokines
  • Headache
  • Mindfulness
  • Randomized controlled trial

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