TY - JOUR
T1 - Mindfulness training does not reduce inflammatory cytokine levels in chronic tension-type headache
AU - Cathcart, Stuart
AU - Vedova, Chris Della
AU - Immink, Maarten
AU - Proeve, Michael
AU - Hayball, John
PY - 2013
Y1 - 2013
N2 - To examine effects of mindfulness training on serum proinflammatory cytokine levels in chronic tension-type headache (CTH) sufferers. Method: Forty-three CTH sufferers participated in a randomized wait-list controlled trial of a mindfulness intervention for headache. Serum concentrations of cytokines IL1-β, IL-2, IL-6, IL-8, IL-12, IL-18, IFN-γ, MCP-1 and TNF-α were measured before and after treatment/wait-list control conditions. Results: Repeated Measures Analysis of Variance revealed that IL1- β, IL-6, IL-8, MCP-1 and TNF-α decreased from pre to post assessments in the treatment and wait-list groups, with no group or group x time effects. Conclusions: Mindfulness training compared to a wait-list control condition does not reduce serum cytokine levels in CTH sufferers.
AB - To examine effects of mindfulness training on serum proinflammatory cytokine levels in chronic tension-type headache (CTH) sufferers. Method: Forty-three CTH sufferers participated in a randomized wait-list controlled trial of a mindfulness intervention for headache. Serum concentrations of cytokines IL1-β, IL-2, IL-6, IL-8, IL-12, IL-18, IFN-γ, MCP-1 and TNF-α were measured before and after treatment/wait-list control conditions. Results: Repeated Measures Analysis of Variance revealed that IL1- β, IL-6, IL-8, MCP-1 and TNF-α decreased from pre to post assessments in the treatment and wait-list groups, with no group or group x time effects. Conclusions: Mindfulness training compared to a wait-list control condition does not reduce serum cytokine levels in CTH sufferers.
KW - Cytokines
KW - Headache
KW - Mindfulness
KW - Randomized controlled trial
UR - http://www.scopus.com/inward/record.url?scp=84892447856&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:84892447856
SN - 1939-5914
VL - 6
SP - 235
EP - 238
JO - Journal of Pain Management
JF - Journal of Pain Management
IS - 3
ER -