Miscellaneous hormones

Matthew Doogue, Morton Burt

    Research output: Chapter in Book/Report/Conference proceedingChapter

    Abstract

    This review of the 2010 publications on adverse reactions to miscellaneous hormones covers calcitonin, gonadotropins (gonadorelin, GNRH, and analogues), gonadotrophin releasing hormone antagonists, somatropin, growth hormone receptor antagonists, melatonin, oxytocin, parathyroid hormone, somatostatin and analogues (lanreotide, octreotide, and pasireotide), vasopressin receptor antagonists (conivaptan, satavaptan, and tolvaptan), and vasopressin and analogues (desmopressin and terlipressin). It also includes a special review on the tumorigenicity of growth hormone. The use of somatostatin analogues was associated with significant malabsorption of fat-soluble vitamins, notably resulting in night blindness, which was reversed by vitamin A supplementation. Concerns about the tumorigenicity of long-term growth hormone prompted two large studies, neither of which showed clear associations; smaller studies continue to be difficult to interpret, owing to potential confounding by other susceptibility factors. Bolus doses of oxytocin were associated with hypotension and only mild hemodynamic reactions were seen with infusions.

    Original languageEnglish
    Title of host publicationSide Effects of Drugs Annual 34
    PublisherElsevier
    Pages703-722
    Number of pages20
    Volume34
    ISBN (Print)9780444594990
    DOIs
    Publication statusPublished - 2012

    Publication series

    NameSide Effects of Drugs Annual
    Volume34
    ISSN (Print)0378-6080

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  • Cite this

    Doogue, M., & Burt, M. (2012). Miscellaneous hormones. In Side Effects of Drugs Annual 34 (Vol. 34, pp. 703-722). (Side Effects of Drugs Annual; Vol. 34). Elsevier. https://doi.org/10.1016/B978-0-444-59499-0.00043-X