Modular light-emitting diode shelving systems for scalable optogenetics

Research output: Working paper/PreprintPreprint

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Optogenetic experiments rely on the controlled delivery of light to diverse biological systems. Impressive devices have been recently developed to simulate cells and small animals with multiple wavelengths and intensities. However, existing hardware solutions are often limited to a single sample holder and their design and cost can further limit scalability. This chapter describes an illumination system that is modular (through the use of accessible components) and scalable (through a shelving structure and low cost). Assembly and operation require no or minimal electrical engineering or programming expertise. Multi-intensity, wavelength and temporal experiments can be performed in dozens of small and large samples. This chapter also introduces methods for temperature and light intensity measurements towards appropriate illumination conditions. This work aims to provide a greater level of accessibility and complementary opportunities for large scale optogenetics in a broad range of biological samples.
Original languageEnglish
PublisherResearch Square
Number of pages21
Publication statusSubmitted - 11 Apr 2023


  • molecular biology
  • Optogenetics
  • Optical control
  • optics
  • illumination hardware
  • LED
  • synthetic biology


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