Molecular characterization of an Australian serotype 1 Streptococcus pneumoniae outbreak

Megan Staples, R Graham, A Jennison, Louis Ariotti, V Hicks, Heather Cook, Victoria Krause, Carolien Giele, H Smith

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    9 Citations (Scopus)

    Abstract

    Serotype 1 Streptococcus pneumoniae is a cause of invasive pneumococcal disease (IPD) worldwide and has been associated with IPD outbreaks, while carriage is rarely detected in healthy adults or children. This study details an Australian multi-state and territory outbreak of serotype 1 S. pneumoniae IPD between 2010 and 2012. Molecular characterization demonstrated the outbreak was largely due to the clonal expansion of sequence type 306, MLVA type 261 S. pneumoniae serotype 1.

    Original languageEnglish
    Pages (from-to)325-333
    Number of pages9
    JournalEpidemiology and Infection
    Volume143
    Issue number2
    DOIs
    Publication statusPublished - 12 Jan 2015

    Keywords

    • IPD
    • outbreak
    • serogroup 1
    • serotype 1
    • Streptococcus pneumoniae

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  • Cite this

    Staples, M., Graham, R., Jennison, A., Ariotti, L., Hicks, V., Cook, H., Krause, V., Giele, C., & Smith, H. (2015). Molecular characterization of an Australian serotype 1 Streptococcus pneumoniae outbreak. Epidemiology and Infection, 143(2), 325-333. https://doi.org/10.1017/S0950268814000648