Molecular cloning and sequencing of the gene encoding a sheep arginine vasopressin type 1a receptor

Anne Marie Hutchins, Paddy A. Phillips, Deon J. Venter, Louise M. Burrell, Colin I. Johnston

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)

Abstract

The gene for the sheep arginine vasopressin type 1a (V1a) receptor subtype was cloned from a genomic library. The deduced amino acid sequence shows characteristics of a G-protein coupled receptor and high sequence identity to human and rat V1a receptor sequences (81% and 73%, respectively). Reverse transcription-polymerase chain reaction (RT-PCR) analysis showed a tissue distribution consistent with a type V1a receptor. The genomic DNA (7.1 kb) contains a 1586 bp intron between the putative 6th and 7th transmembrane domains.

Original languageEnglish
Pages (from-to)266-270
Number of pages5
JournalBBA - Gene Structure and Expression
Volume1263
Issue number3
DOIs
Publication statusPublished - 19 Sep 1995
Externally publishedYes

Keywords

  • Arginine vasopressin
  • Genomic DNA sequence
  • Type 1a receptor

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