Molecular-Genetic Basis of Plant Breeding

Elena Khlestkina, Yuri Shavrukov

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Traditional plant breeding can be improved significantly through the application of molecular and genetic approaches. Starting from the basis of molecular markers and marker-assisted selection, these methods are becoming increasingly common in crop breeding. Whether it be plant genotyping focused on individual genes in an experiment or on thousands of genes simultaneously in microarray, these methods are integral to the progression of modern plant breeding programs. Crosses and segregations can be used to generate various types of doubled haploid and recombinant inbred lines, but genome-wide association mapping presents a powerful tool for comparative molecular-genetic analysis without hybridization. Expression of the identified genes can also be studied in individual analyses or through RNA-seq methods; these tools are very informative for plant breeding. An important component of modern plant breeding deals with proteomics and other biomolecules. Analyses of individual polypeptides and screens comparing the different profiles of a wide variety of proteins improve our knowledge of the molecular-genetic basis of plant biology as applied to crop breeding.
Original languageEnglish
Article number1392
Number of pages2
Issue number10
Publication statusPublished - Oct 2022


  • Genetics
  • Plants
  • Plant Breeding


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