Molecular typing of cryoglobulins by mass spectrometry

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4 Citations (Scopus)


A cause of potentially devastating pathologies, cryoglobulins are immunoglobulin complexes that precipitate out of serum at temperatures lower than 37°C. They often arise secondary to underlying conditions, such as hepatitis infections, although may be idiopathic. Brouet et al 1 classified cryoglobulins according to their immunoglobulin composition: type I (monoclonal), type II (mixed with monoclonal rheumatoid factor (RF)) and type III (mixed with polyclonal RF).
Original languageEnglish
Pages (from-to)163-164
Number of pages2
JournalAnnals of the Rheumatic Diseases
Issue number1
Publication statusPublished - Jan 2020


  • autoantibodies
  • autoimmune diseases
  • autoimmunity
  • rheumatoid factor
  • Sjøgren's syndrome


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