Monosodium urate crystals in asymptomatic knee joints

T. Gordon, J. V. Bertouch, B. R. Walsh, P. M. Brooks

Research output: Contribution to journalArticlepeer-review

31 Citations (Scopus)


Monosodium urate (MSU) crystals were shown in synovial (SF) fluid taken from the asymptomatic knee joints of 11 out of 13 patients with tophaceous gout. Intracellular crystals were identified in some cases. Examination of synovial biopsies taken concurrently revealed MSU crystals in 2 out of 6 cases. The results show that MSU crystals can be found in SF and synovium in the absence of acute gout. This implies that additional factors are important in the pathogenesis of gouty inflammation.

Original languageEnglish
Pages (from-to)967-969
Number of pages3
JournalJournal of Rheumatology
Issue number6
Publication statusPublished - 1 Dec 1982
Externally publishedYes


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