Motility of the left colon in children and adolescents with functional constipation: a retrospective comparison between solid-state and water-perfused colonic manometry

I J N Koppen, L Wiklendt, D Yacob, C Di Lorenzo, M A Benninga, P G Dinning

Research output: Contribution to journalArticle

5 Citations (Scopus)
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Abstract

Background: Using water-perfused (WP) high-resolution manometry, we recently demonstrated that children with functional constipation (FC) lacked the postprandial increase in distal colonic cyclic motor patterns that was observed in healthy adults. Our aim was to determine if similar results could be detected using a solid-state (SS) manometry catheter. Methods: We performed a retrospective analysis of 19 children with FC (median age 11.1 years, 58% male) who underwent colonic manometry with a SS catheter (36 sensors, 3 cm apart). Data were compared with previously published data using a WP catheter (36 sensors, 1.5 cm apart) recorded from 18 children with FC (median age 15 years; 28% male). Key Results: The cyclic motor patterns recorded by the SS catheter did not differ from those previously recorded by the WP catheter. There was no detected increase in this activity in response to the meal in either group. Long-single motor patterns were recorded in most patients (n = 16, 84%) with the SS catheter. The number of these events did not differ from the WP recordings. In the SS data, HAPCs were observed in 4 children prior to the meal, in 5 after the meal. This did not differ significantly from the WP data. Conclusions & Inferences: These data recorded by SS manometry did not differ from WP manometry data. Regardless of the catheter used, both studies revealed an abnormal colonic response to a meal, indicating a pathology which is not related to the catheter used to record these data.

Original languageEnglish
Article numbere13401
Number of pages9
JournalNeurogastroenterology and Motility
Volume30
Issue number9
DOIs
Publication statusPublished - Sep 2018

Bibliographical note

© 2018 The Authors. Neurogastroenterology & Motility Published by John Wiley & Sons, Ltd.

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

Keywords

  • children
  • colonic manometry
  • constipation
  • motility

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