MUTATION FREQUENCY IN NURSES AND PHARMACISTS WORKING WITH CYTOTOXIC DRUGS

A. CHRYSOSTOMOU; R. SESHADRI; A. A. MORLEY

doi:10.1111/j.1445-5994.1984.tb03782.x

MUTATION FREQUENCY IN NURSES AND PHARMACISTS WORKING WITH CYTOTOXIC DRUGS

A. CHRYSOSTOMOU, R. SESHADRI, A. A. MORLEY

Research output: Contribution to journal › Article › peer-review

47 Citations (Scopus)

Abstract

Individuals occupationally exposed to cytotoxic drugs may be at risk owing to the effects of these agents on DNA. As an index of DNA damage, in vivo mutations were measured in lymphocytes from 24 oncology nurses or pharmacists and 24 matched controls. Mutation frequency was significantly increased in exposed individuals and appeared to be related to duration of exposure. However, the overall magnitude of the increase was small and its biological significance remains to be determined.

Original language	English
Pages (from-to)	831-834
Number of pages	4
Journal	Australian and New Zealand Journal of Medicine
Volume	14
Issue number	6
DOIs	https://doi.org/10.1111/j.1445-5994.1984.tb03782.x
Publication status	Published - Dec 1984

Keywords

cytotoxic drugs
lymphocytes
Mutations
nurses
occupational health
pharmacists

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MUTATION FREQUENCY IN NURSES AND PHARMACISTS WORKING WITH CYTOTOXIC DRUGS

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