Nanofibrillar thermoreversible micellar microgels

Diego Velasco, Mokit Chau, Héloïse Thérien-Aubin, Alexander Kumachev, Ethan Tumarkin, Zhongfan Jia, Gilbert C. Walker, Michael J. Monteiro, Eugenia Kumacheva

Research output: Contribution to journalArticlepeer-review

15 Citations (Scopus)

Abstract

By using microfluidics, we generated micellar nanofibrillar microgels from solutions of worm-like micelles of poly(N-isopropyl acrylamide)-block- polystyrene. The microgels were formed under physiological conditions (pH = 7.4, 37 °C) and rapidly dissociated upon cooling to 25-27 °C, thereby enabling cell encapsulation and release for further characterization. Our work offers a new concept for the generation of dynamic artificial three-dimensional microenvironments for studies of cell fate.

Original languageEnglish
Pages (from-to)2380-2383
Number of pages4
JournalSoft Matter
Volume9
Issue number8
DOIs
Publication statusPublished - 28 Feb 2013
Externally publishedYes

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