Narcolepsy: Comorbidities, complexities and future directions

Sajni Gudka, Emma Haynes, Joanne Scotney, Sutapa Mukherjee, Simon Frenkel, Sheila Sivam, John Swieca, Ksenia Chamula, David Cunnington, Bandana Saini

Research output: Contribution to journalReview articlepeer-review

6 Citations (Scopus)


Patients with narcolepsy live with a lifelong sleep-wake disorder, impairing their quality of life, productivity, educational and employment outcomes. Clinicians are becoming aware that a significant aspect of the burden of this disease relates to frequent comorbid conditions, including aspects of the patient's emotional, metabolic, sleep and immune health. This review explores the literature describing the comorbidities seen in patients with narcolepsy, to enhance understanding of these often complex presentations. It hopes to encourage a multidisciplinary approach, to collaborate with patients and a broad clinical team, and to maximise clinical and quality of life outcomes, for those living with narcolepsy.

Original languageEnglish
Article number101669
Number of pages10
JournalSleep Medicine Reviews
Publication statusPublished - Oct 2022


  • Cataplexy
  • Chronic disease
  • Comorbidity
  • Hypersomnia
  • Literature review
  • Multidisciplinary
  • Narcolepsy
  • Sleep disorders


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