Needleless connector decontamination for prevention of central venous access device infection: A pilot randomized controlled trial

Claire M. Rickard; Julie Flynn; Emily Larsen; Gabor Mihala; E. Geoffrey Playford; Joanie Shaw; Samantha Keogh; Amanda Ullman; Li Zhang; Nicole Gavin; Tricia Kleidon; Vineet Chopra; Alexandra L. McCarthy; Patricia Kuerten Rocha; Nicole Marsh

doi:10.1016/j.ajic.2020.07.026

Needleless connector decontamination for prevention of central venous access device infection: A pilot randomized controlled trial

Claire M. Rickard
, Julie Flynn
, Emily Larsen
, Gabor Mihala
, E. Geoffrey Playford
, Joanie Shaw
, Samantha Keogh
, Amanda Ullman
, Li Zhang
, Nicole Gavin
, Tricia Kleidon
, Vineet Chopra
, Alexandra L. McCarthy
, Patricia Kuerten Rocha
, Nicole Marsh

Research output: Contribution to journal › Article › peer-review

25 Citations (Scopus)

1 Downloads (Pure)

Abstract

Pilot randomized controlled trial (180 patients) of needleless connector decontamination. Central line-associated bloodstream infection occurred in 2% (1/61) of 70% isopropyl alcohol (IPA) wipe, 2% (1/59) of 70% IPA cap, and zero (0/58) infections in 2% chlorhexidine gluconate in 70% IPA wipe patients. Larger definitive trials are feasible and needed.

Original language	English
Pages (from-to)	269-273
Number of pages	5
Journal	American Journal of Infection Control
Volume	49
Issue number	2
DOIs	https://doi.org/10.1016/j.ajic.2020.07.026
Publication status	Published - Feb 2021
Externally published	Yes

Keywords

Catheter related infections
Catheterization
Central venous
Chlorhexidine gluconate
Infection control
Isopropyl alcohol

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10.1016/j.ajic.2020.07.026Licence: CC BY-NC-ND

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Rickard, C. M., Flynn, J., Larsen, E., Mihala, G., Playford, E. G., Shaw, J., Keogh, S., Ullman, A., Zhang, L., Gavin, N., Kleidon, T., Chopra, V., McCarthy, A. L., Rocha, P. K., & Marsh, N. (2021). Needleless connector decontamination for prevention of central venous access device infection: A pilot randomized controlled trial. American Journal of Infection Control, 49(2), 269-273. https://doi.org/10.1016/j.ajic.2020.07.026

@article{b2aa5c894b6248ddb749d945830ffa6a,

title = "Needleless connector decontamination for prevention of central venous access device infection: A pilot randomized controlled trial",

abstract = "Pilot randomized controlled trial (180 patients) of needleless connector decontamination. Central line-associated bloodstream infection occurred in 2\% (1/61) of 70\% isopropyl alcohol (IPA) wipe, 2\% (1/59) of 70\% IPA cap, and zero (0/58) infections in 2\% chlorhexidine gluconate in 70\% IPA wipe patients. Larger definitive trials are feasible and needed.",

keywords = "Catheter related infections, Catheterization, Central venous, Chlorhexidine gluconate, Infection control, Isopropyl alcohol",

author = "Rickard, \{Claire M.\} and Julie Flynn and Emily Larsen and Gabor Mihala and Playford, \{E. Geoffrey\} and Joanie Shaw and Samantha Keogh and Amanda Ullman and Li Zhang and Nicole Gavin and Tricia Kleidon and Vineet Chopra and McCarthy, \{Alexandra L.\} and Rocha, \{Patricia Kuerten\} and Nicole Marsh",

year = "2021",

month = feb,

doi = "10.1016/j.ajic.2020.07.026",

language = "English",

volume = "49",

pages = "269--273",

journal = "American Journal of Infection Control",

issn = "0196-6553",

publisher = "Elsevier Inc.",

number = "2",

}

Rickard, CM, Flynn, J, Larsen, E, Mihala, G, Playford, EG, Shaw, J, Keogh, S, Ullman, A, Zhang, L, Gavin, N, Kleidon, T, Chopra, V, McCarthy, AL, Rocha, PK & Marsh, N 2021, 'Needleless connector decontamination for prevention of central venous access device infection: A pilot randomized controlled trial', American Journal of Infection Control, vol. 49, no. 2, pp. 269-273. https://doi.org/10.1016/j.ajic.2020.07.026

TY - JOUR

T1 - Needleless connector decontamination for prevention of central venous access device infection

T2 - A pilot randomized controlled trial

AU - Rickard, Claire M.

AU - Flynn, Julie

AU - Larsen, Emily

AU - Mihala, Gabor

AU - Playford, E. Geoffrey

AU - Shaw, Joanie

AU - Keogh, Samantha

AU - Ullman, Amanda

AU - Zhang, Li

AU - Gavin, Nicole

AU - Kleidon, Tricia

AU - Chopra, Vineet

AU - McCarthy, Alexandra L.

AU - Rocha, Patricia Kuerten

AU - Marsh, Nicole

PY - 2021/2

Y1 - 2021/2

N2 - Pilot randomized controlled trial (180 patients) of needleless connector decontamination. Central line-associated bloodstream infection occurred in 2% (1/61) of 70% isopropyl alcohol (IPA) wipe, 2% (1/59) of 70% IPA cap, and zero (0/58) infections in 2% chlorhexidine gluconate in 70% IPA wipe patients. Larger definitive trials are feasible and needed.

AB - Pilot randomized controlled trial (180 patients) of needleless connector decontamination. Central line-associated bloodstream infection occurred in 2% (1/61) of 70% isopropyl alcohol (IPA) wipe, 2% (1/59) of 70% IPA cap, and zero (0/58) infections in 2% chlorhexidine gluconate in 70% IPA wipe patients. Larger definitive trials are feasible and needed.

KW - Catheter related infections

KW - Catheterization

KW - Central venous

KW - Chlorhexidine gluconate

KW - Infection control

KW - Isopropyl alcohol

UR - https://www.scopus.com/pages/publications/85089859763

U2 - 10.1016/j.ajic.2020.07.026

DO - 10.1016/j.ajic.2020.07.026

M3 - Article

C2 - 32735809

AN - SCOPUS:85089859763

SN - 0196-6553

VL - 49

SP - 269

EP - 273

JO - American Journal of Infection Control

JF - American Journal of Infection Control

IS - 2

ER -

Needleless connector decontamination for prevention of central venous access device infection: A pilot randomized controlled trial

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Keywords

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