New insights in gastroesophageal reflux, esophageal function and gastric emptying in relation to dysphagia before and after anti-reflux surgery in children topical collection on pediatric gastroenterology

M Smits, C Loots, M Benninga, T Omari, M van Wijk

    Research output: Contribution to journalArticle

    3 Citations (Scopus)

    Abstract

    In children with gastroesophageal reflux (GER) disease refractory to pharmacological therapies, anti-reflux surgery (fundoplication) may be a treatment of last resort. The applicability of fundoplication has been hampered by the inability to predict which patient may benefit from surgery and which patient is likely to develop post-operative dysphagia. pH impedance measurement and conventional manometry are unable to predict dysphagia, while the role of gastric emptying remains poorly understood. Recent data suggest that the selection of patients who will benefit from surgery might be enhanced by automated impedance manometry pressure-flow analysis (AIM) analysis, which relates bolus movement and pressure generation within the esophageal lumen.

    Original languageEnglish
    Article number351
    Pages (from-to)351-351
    Number of pages6
    JournalCurrent Gastroenterology Reports
    Volume15
    Issue number10
    DOIs
    Publication statusPublished - 2013

    Keywords

    • AIM analysis
    • Children
    • Dysphagia
    • Fundoplication
    • Gastroesophageal reflux disease

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