TY - JOUR
T1 - Nightly Variation in Sleep Apnea Severity as Atrial Fibrillation Risk
AU - Linz, Dominik
AU - Brooks, Anthony G.
AU - Elliott, Adrian D.
AU - Kalman, Jonathan M.
AU - McEvoy, R. Doug
AU - Lau, Dennis H.
AU - Sanders, Prashanthan
PY - 2018/11/6
Y1 - 2018/11/6
N2 - Sleep-disordered breathing (SDB) severity is largely determined by the number of apneas and hypopneas/h during a single overnight sleep study, following which patients are categorized as no, mild, moderate, or severe SDB (1). However, SDB severity in an individual patient may not be stable over time, but may instead exhibit a considerable night-to-night variability, which might result in a dynamic exposure to SDB-related conditions affecting the timing and extent of cardiovascular responses such as atrial fibrillation (AF) (2). Although chronic atrial structural alterations have already been described in AF patients with SDB (3), clinical evidence for a dynamic AF substrate related to nightly SDB severity is lacking.
AB - Sleep-disordered breathing (SDB) severity is largely determined by the number of apneas and hypopneas/h during a single overnight sleep study, following which patients are categorized as no, mild, moderate, or severe SDB (1). However, SDB severity in an individual patient may not be stable over time, but may instead exhibit a considerable night-to-night variability, which might result in a dynamic exposure to SDB-related conditions affecting the timing and extent of cardiovascular responses such as atrial fibrillation (AF) (2). Although chronic atrial structural alterations have already been described in AF patients with SDB (3), clinical evidence for a dynamic AF substrate related to nightly SDB severity is lacking.
UR - http://www.scopus.com/inward/record.url?scp=85055181391&partnerID=8YFLogxK
U2 - 10.1016/j.jacc.2018.08.2159
DO - 10.1016/j.jacc.2018.08.2159
M3 - Letter
C2 - 30384896
AN - SCOPUS:85055181391
SN - 0735-1097
VL - 72
SP - 2406
EP - 2407
JO - Journal of The American College of Cardiology
JF - Journal of The American College of Cardiology
IS - 19
ER -