TY - JOUR
T1 - Nocebo effects on informed consent within medical and psychological settings
T2 - A scoping review
AU - Stirling, Nadine S.J.
AU - Bridgland, Victoria M.E.
AU - Takarangi, Melanie K.T.
PY - 2022/6/8
Y1 - 2022/6/8
N2 - Warning research participants and patients about potential risks associated with participation/treatment is a fundamental part of consent. However, such risk warnings might cause negative expectations and subsequent nocebo effects (i.e., negative expectations cause negative outcomes) in participants. Because no existing review documents how past research has quantitatively examined nocebo effects–and negative expectations–arising from consent risk warnings, we conducted a pre-registered scoping review (N = 9). We identified several methodological issues across these studies, which in addition to mixed findings, limit conclusions about whether risk warnings cause nocebo effects.
AB - Warning research participants and patients about potential risks associated with participation/treatment is a fundamental part of consent. However, such risk warnings might cause negative expectations and subsequent nocebo effects (i.e., negative expectations cause negative outcomes) in participants. Because no existing review documents how past research has quantitatively examined nocebo effects–and negative expectations–arising from consent risk warnings, we conducted a pre-registered scoping review (N = 9). We identified several methodological issues across these studies, which in addition to mixed findings, limit conclusions about whether risk warnings cause nocebo effects.
KW - ethics
KW - Informed consent
KW - negative expectations
KW - nocebo effects
UR - http://www.scopus.com/inward/record.url?scp=85131680486&partnerID=8YFLogxK
U2 - 10.1080/10508422.2022.2081853
DO - 10.1080/10508422.2022.2081853
M3 - Article
AN - SCOPUS:85131680486
JO - Ethics and Behavior
JF - Ethics and Behavior
SN - 1050-8422
ER -