Non-vascular drug eluting stents as localized controlled drug delivery platform: Preclinical and clinical experience

Mohsin Shaikh, Ganessan Kichenadasse, Namita Choudhury, Ross Butler, Sanjay Garg

    Research output: Contribution to journalReview article

    24 Citations (Scopus)

    Abstract

    Stents occupy an important place in the medical field for their widespread application. They have been used in vascular as well as in non-vascular organs for various reasons. Among vascular stents, development of coronary drug eluting stents (DESs) has completely revolutionised the percutaneous coronary intervention. Similarly, attempts have been made to make use of this modality in non-vascular organs. This paper focuses on the preclinical and clinical experience with drug-eluting non-vascular stents with emphasis on drug delivery systems and regulatory requirements for their development.

    Original languageEnglish
    Pages (from-to)105-117
    Number of pages13
    JournalJournal of Controlled Release
    Volume172
    Issue number1
    DOIs
    Publication statusPublished - 2013

    Keywords

    • Clinical trials
    • Drug eluting stents
    • Non-vascular stents
    • Preclinical studies

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