Non-vascular drug eluting stents as localized controlled drug delivery platform: Preclinical and clinical experience

Mohsin Shaikh; Ganessan Kichenadasse; Namita Choudhury; Ross Butler; Sanjay Garg

doi:10.1016/j.jconrel.2013.08.010

Non-vascular drug eluting stents as localized controlled drug delivery platform: Preclinical and clinical experience

Mohsin Shaikh, Ganessan Kichenadasse, Namita Choudhury, Ross Butler, Sanjay Garg

Research output: Contribution to journal › Review article › peer-review

43 Citations (Scopus)

Abstract

Stents occupy an important place in the medical field for their widespread application. They have been used in vascular as well as in non-vascular organs for various reasons. Among vascular stents, development of coronary drug eluting stents (DESs) has completely revolutionised the percutaneous coronary intervention. Similarly, attempts have been made to make use of this modality in non-vascular organs. This paper focuses on the preclinical and clinical experience with drug-eluting non-vascular stents with emphasis on drug delivery systems and regulatory requirements for their development.

Original language	English
Pages (from-to)	105-117
Number of pages	13
Journal	Journal of Controlled Release
Volume	172
Issue number	1
DOIs	https://doi.org/10.1016/j.jconrel.2013.08.010
Publication status	Published - 2013

Keywords

Clinical trials
Drug eluting stents
Non-vascular stents
Preclinical studies

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.jconrel.2013.08.010

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title = "Non-vascular drug eluting stents as localized controlled drug delivery platform: Preclinical and clinical experience",

abstract = "Stents occupy an important place in the medical field for their widespread application. They have been used in vascular as well as in non-vascular organs for various reasons. Among vascular stents, development of coronary drug eluting stents (DESs) has completely revolutionised the percutaneous coronary intervention. Similarly, attempts have been made to make use of this modality in non-vascular organs. This paper focuses on the preclinical and clinical experience with drug-eluting non-vascular stents with emphasis on drug delivery systems and regulatory requirements for their development.",

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AU - Shaikh, Mohsin

AU - Kichenadasse, Ganessan

AU - Choudhury, Namita

AU - Butler, Ross

AU - Garg, Sanjay

PY - 2013

Y1 - 2013

N2 - Stents occupy an important place in the medical field for their widespread application. They have been used in vascular as well as in non-vascular organs for various reasons. Among vascular stents, development of coronary drug eluting stents (DESs) has completely revolutionised the percutaneous coronary intervention. Similarly, attempts have been made to make use of this modality in non-vascular organs. This paper focuses on the preclinical and clinical experience with drug-eluting non-vascular stents with emphasis on drug delivery systems and regulatory requirements for their development.

AB - Stents occupy an important place in the medical field for their widespread application. They have been used in vascular as well as in non-vascular organs for various reasons. Among vascular stents, development of coronary drug eluting stents (DESs) has completely revolutionised the percutaneous coronary intervention. Similarly, attempts have been made to make use of this modality in non-vascular organs. This paper focuses on the preclinical and clinical experience with drug-eluting non-vascular stents with emphasis on drug delivery systems and regulatory requirements for their development.

KW - Clinical trials

KW - Drug eluting stents

KW - Non-vascular stents

KW - Preclinical studies

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U2 - 10.1016/j.jconrel.2013.08.010

DO - 10.1016/j.jconrel.2013.08.010

M3 - Review article

SN - 0168-3659

VL - 172

SP - 105

EP - 117

JO - Journal of Controlled Release

JF - Journal of Controlled Release

IS - 1

ER -

Non-vascular drug eluting stents as localized controlled drug delivery platform: Preclinical and clinical experience

Abstract

Keywords

UN SDGs

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