Nonsynonymous polymorphism in guanine monophosphate synthetase is a risk factor for unfavorable thiopurine metabolite ratios in patients with inflammatory bowel disease

Rebecca L. Roberts, Mary C. Wallace, Margien L. Seinen, Adriaan A. van Bodegraven, Krupa Krishnaprasad, Gregory T. Jones, Andre M. van Rij, Angela Baird, Ian C. Lawrance, Ruth Prosser, Peter Bampton, Rachel Grafton, Lisa A. Simms, Corrie Studd, Sally J. Bell, Martin A. Kennedy, Jacob Halliwell, Richard B. Gearry, Graham Radford-Smith, Jane M. AndrewsPatrick C. McHugh, Murray L. Barclay

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Biochemistry, Genetics and Molecular Biology