Novel and emerging therapies

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review



Nasal continuous positive airway pressure (CPAP) remains the gold standard treatment for moderate–severe obstructive sleep apnoea (OSA), but patient acceptance and adherence to the therapy is often poor. Consequently, there has been great interest in developing alternative therapies for OSA. The mechanisms of action, strengths, and weaknesses of three such therapies are discussed in this chapter: hypoglossal nerve stimulation, nasal positive end-expiratory pressure valves, and oral pressure therapy.
Original languageEnglish
Title of host publicationSleep Medicine
EditorsDarren R Mansfield, Nick Antic, Shantha M W Rajaratnam, Matthew T Naughton
Place of PublicationMelbourne
PublisherIP Communications
Number of pages5
ISBN (Electronic)9780995388710
ISBN (Print)9780995388703
Publication statusPublished - Apr 2017
Externally publishedYes


  • Nasal continuous positive airway pressure (CPAP)
  • obstructive sleep apnoea (OSA)
  • alternative therapies for OSA
  • hypoglossal nerve stimulation
  • nasal positive end-expiratory pressure valves
  • oral pressure therapy


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