Novel cytotoxicity associated with Anabaena circinalis 131C

Suzanne Froscio; Kimberly Sieburn; H-M Lau; Andrew Humpage

doi:10.1016/j.toxicon.2011.09.007

Novel cytotoxicity associated with Anabaena circinalis 131C

Suzanne Froscio, Kimberly Sieburn, H-M Lau, Andrew Humpage

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

The production of secondary metabolites by cyanobacteria is extensively varied. Anabaena spp. have been shown to produce the toxins saxitoxin, anatoxin-a, anatoxin-a(s), cylindrospermopsin and microcystin. In this study we show cytotoxicity associated with Anabaena circinalis 131C that could not be attributed to its high saxitoxin content. Analytical, ELISA and enzymatic methods excluded the presence of other known cyanobacterial toxins leading to the suggestion of novel toxicity.

Original language	English
Pages (from-to)	689-692
Number of pages	4
Journal	Toxicon
Volume	58
Issue number	8
DOIs	https://doi.org/10.1016/j.toxicon.2011.09.007
Publication status	Published - 1 Dec 2011

Keywords

Cyanobacteria
Cyanotoxin
Metabolic activity

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10.1016/j.toxicon.2011.09.007

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title = "Novel cytotoxicity associated with Anabaena circinalis 131C",

abstract = "The production of secondary metabolites by cyanobacteria is extensively varied. Anabaena spp. have been shown to produce the toxins saxitoxin, anatoxin-a, anatoxin-a(s), cylindrospermopsin and microcystin. In this study we show cytotoxicity associated with Anabaena circinalis 131C that could not be attributed to its high saxitoxin content. Analytical, ELISA and enzymatic methods excluded the presence of other known cyanobacterial toxins leading to the suggestion of novel toxicity.",

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author = "Suzanne Froscio and Kimberly Sieburn and H-M Lau and Andrew Humpage",

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AU - Froscio, Suzanne

AU - Sieburn, Kimberly

AU - Lau, H-M

AU - Humpage, Andrew

PY - 2011/12/1

Y1 - 2011/12/1

N2 - The production of secondary metabolites by cyanobacteria is extensively varied. Anabaena spp. have been shown to produce the toxins saxitoxin, anatoxin-a, anatoxin-a(s), cylindrospermopsin and microcystin. In this study we show cytotoxicity associated with Anabaena circinalis 131C that could not be attributed to its high saxitoxin content. Analytical, ELISA and enzymatic methods excluded the presence of other known cyanobacterial toxins leading to the suggestion of novel toxicity.

AB - The production of secondary metabolites by cyanobacteria is extensively varied. Anabaena spp. have been shown to produce the toxins saxitoxin, anatoxin-a, anatoxin-a(s), cylindrospermopsin and microcystin. In this study we show cytotoxicity associated with Anabaena circinalis 131C that could not be attributed to its high saxitoxin content. Analytical, ELISA and enzymatic methods excluded the presence of other known cyanobacterial toxins leading to the suggestion of novel toxicity.

KW - Cyanobacteria

KW - Cyanotoxin

KW - Metabolic activity

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U2 - 10.1016/j.toxicon.2011.09.007

DO - 10.1016/j.toxicon.2011.09.007

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SN - 0041-0101

VL - 58

SP - 689

EP - 692

JO - Toxicon

JF - Toxicon

IS - 8

ER -

Novel cytotoxicity associated with Anabaena circinalis 131C

Abstract

Keywords

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