Nutritional regulation of insulin-like growth factor-I mRNA expression in barramundi, Lates calcarifer

S J Matthews, A. K. K. Kinhult, P Hoeben, V. K. Sara, T. A. Anderson

Research output: Contribution to journalArticlepeer-review

32 Citations (Scopus)

Abstract

The effect of nutritional status on IGF-I mRNA expression in the liver and brain of juvenile barramundi (Lates calcarifer) was investigated. Fish were either fed a satiety ration (SAT) or starved (STV) for 6 weeks. Starved fish demonstrated significantly lower condition factor and hepatic IGF-I mRNA expression at 3 and 6 weeks, when compared with the SAT group. IGF-I mRNA expression in the brain was 10 fold lower than the liver and was not affected by ration size. These results suggest the liver is the major site of IGF-I mRNA synthesis and hepatic but not brain IGF-I mRNA expression is regulated by food availability in juvenile barramundi
Original languageEnglish
Pages (from-to)273-276
Number of pages4
JournalJournal of Molecular Endocrinology
Volume18
Issue number3
DOIs
Publication statusPublished - Jun 1997
Externally publishedYes

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