Obstructive Sleep Apnoea: From pathogenesis to treatment: Current controversies and future directions

Peter Eastwood; A Malhotra; Lyle Palmer; E Kezirian; Richard Horner; Mary Ip; Robert Thurnheer; Nicholas Antic; D Hillman

doi:10.1111/j.1440-1843.2009.01699.x

Obstructive Sleep Apnoea: From pathogenesis to treatment: Current controversies and future directions

Peter Eastwood, A Malhotra, Lyle Palmer, E Kezirian, Richard Horner, Mary Ip, Robert Thurnheer, Nicholas Antic, D Hillman

Research output: Contribution to journal › Review article › peer-review

91 Citations (Scopus)

Abstract

Obstructive sleep apnoea (OSA) is a common disease, recognized as an independent risk factor for a range of clinical conditions, such as hypertension, stroke, depression and diabetes. Despite extensive research over the past two decades, the mechanistic links between OSA and other associated clinical conditions, including metabolic disorders and cardiovascular disease, remain unclear. Indeed, the pathogenesis of OSA itself remains incompletely understood. This review provides opinions from a number of leading experts on issues related to OSA and its pathogenesis, interaction with anaesthesia, metabolic consequences and comorbidities, cardiovascular disease, genetics, measurement and diagnosis, surgical treatment and pharmacotherapeutic targets.

Original language	English
Pages (from-to)	587-595
Number of pages	9
Journal	Respirology
Volume	15
Issue number	4
DOIs	https://doi.org/10.1111/j.1440-1843.2009.01699.x
Publication status	Published - May 2010

Keywords

Pathogenesis
Sleep apnoea syndrome
Treatment

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1111/j.1440-1843.2009.01699.x

Cite this

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abstract = "Obstructive sleep apnoea (OSA) is a common disease, recognized as an independent risk factor for a range of clinical conditions, such as hypertension, stroke, depression and diabetes. Despite extensive research over the past two decades, the mechanistic links between OSA and other associated clinical conditions, including metabolic disorders and cardiovascular disease, remain unclear. Indeed, the pathogenesis of OSA itself remains incompletely understood. This review provides opinions from a number of leading experts on issues related to OSA and its pathogenesis, interaction with anaesthesia, metabolic consequences and comorbidities, cardiovascular disease, genetics, measurement and diagnosis, surgical treatment and pharmacotherapeutic targets.",

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AU - Horner, Richard

AU - Ip, Mary

AU - Thurnheer, Robert

AU - Antic, Nicholas

AU - Hillman, D

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Obstructive Sleep Apnoea: From pathogenesis to treatment: Current controversies and future directions

Abstract

Keywords

UN SDGs

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