Omalizumab-induced ocular myasthenia gravis?

Hanru Wang, Devaraj Supramaniam, Sudha Cugati, Celia Chen

Research output: Contribution to journalLetterpeer-review

Abstract

Drug-induced myasthenia gravis (MG) can be caused by various classes of medications, and many therapeutic agents have been known to interfere directly with neuromuscular transmission by affecting either presynaptic or postsynaptic function.1 Omalizumab is a recombinant DNA-derived humanized immunoglobulin (Ig) G1 monoclonal antibody specifically designed to bind to free human IgE and a membrane-bound form of IgE on B lymphocytes; it is used in the treatment of allergic asthma and chronic urticaria.2 We report a case of omalizumab-induced MG with a positive challenge–rechallenge response.
Original languageEnglish
Pages (from-to)e630-e632
Number of pages3
JournalCanadian Journal of Ophthalmology
Volume59
Issue number5
Early online date14 Apr 2024
DOIs
Publication statusPublished - Oct 2024

Keywords

  • Myasthenia gravis
  • Eye
  • Omalizumab

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