Optimal Conduit Diameter Selection in Coronary Bypass Grafting Using Saphenous Vein

Malgorzata (Maggie) Szpytma; Robert A. Baker; Damian Gimpel; Richard F. Newland; David G. Lance; Gregory D. Rice; Gareth Crouch; Jayme S. Bennetts

doi:10.1016/j.hlc.2024.01.035

Optimal Conduit Diameter Selection in Coronary Bypass Grafting Using Saphenous Vein

Malgorzata (Maggie) Szpytma, Robert A. Baker, Damian Gimpel, Richard F. Newland, David G. Lance, Gregory D. Rice, Gareth Crouch, Jayme S. Bennetts

College of Medicine and Public Health

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

Background: Predictors of long-term saphenous vein graft (SVG) patency following coronary artery bypass grafting (CABG) include harvesting technique, degree of proximal coronary stenosis, and target vessel diameter and runoff. The objective of this study was to evaluate the association between vein graft diameter and long-term survival.

Methods: Patients undergoing primary CABG (2000–2017) at Flinders Medical Centre, Adelaide, Australia, were categorised into three groups according to average SVG diameter (<3.5 mm [small], 3.5–4 mm [medium], >4 mm [large]). Survival data was obtained from the Australian Institute of Health and Welfare National Death Index. To determine the association of SVG diameter with long-term survival we used Kaplan-Meier survival analysis and Cox proportional hazard models adjusted for preoperative variables associated with survival.

Results: Vein graft diameter was collected in 3,797 patients. Median follow-up time was 7.6 years (interquartile range, 3.9–11.8) with 1,377 deaths. SVG size >4 mm was associated with lower rates of adjusted survival up to 4 years postoperatively (hazard ratio 1.48; 95% confidence interval 1.05–2.1; p=0.026).

Conclusions: Vein graft diameter >4mm was found to be associated with lower rates of survival following CABG.

Original language	English
Pages (from-to)	898-907
Number of pages	10
Journal	Heart Lung and Circulation
Volume	33
Issue number	6
Early online date	7 Mar 2024
DOIs	https://doi.org/10.1016/j.hlc.2024.01.035
Publication status	Published - Jun 2024

Keywords

Bypass
Conduit
Coronary
Diameter
Saphenous vein

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@article{03793323f4054680a1b46a9e6aaba1bb,

title = "Optimal Conduit Diameter Selection in Coronary Bypass Grafting Using Saphenous Vein",

abstract = "Background: Predictors of long-term saphenous vein graft (SVG) patency following coronary artery bypass grafting (CABG) include harvesting technique, degree of proximal coronary stenosis, and target vessel diameter and runoff. The objective of this study was to evaluate the association between vein graft diameter and long-term survival. Methods: Patients undergoing primary CABG (2000–2017) at Flinders Medical Centre, Adelaide, Australia, were categorised into three groups according to average SVG diameter (<3.5 mm [small], 3.5–4 mm [medium], >4 mm [large]). Survival data was obtained from the Australian Institute of Health and Welfare National Death Index. To determine the association of SVG diameter with long-term survival we used Kaplan-Meier survival analysis and Cox proportional hazard models adjusted for preoperative variables associated with survival. Results: Vein graft diameter was collected in 3,797 patients. Median follow-up time was 7.6 years (interquartile range, 3.9–11.8) with 1,377 deaths. SVG size >4 mm was associated with lower rates of adjusted survival up to 4 years postoperatively (hazard ratio 1.48; 95% confidence interval 1.05–2.1; p=0.026). Conclusions: Vein graft diameter >4mm was found to be associated with lower rates of survival following CABG.",

keywords = "Bypass, Conduit, Coronary, Diameter, Saphenous vein",

author = "Szpytma, {Malgorzata (Maggie)} and Baker, {Robert A.} and Damian Gimpel and Newland, {Richard F.} and Lance, {David G.} and Rice, {Gregory D.} and Gareth Crouch and Bennetts, {Jayme S.}",

year = "2024",

month = jun,

doi = "10.1016/j.hlc.2024.01.035",

language = "English",

volume = "33",

pages = "898--907",

journal = "Heart Lung and Circulation",

issn = "1443-9506",

publisher = "Elsevier Australia",

number = "6",

}

TY - JOUR

T1 - Optimal Conduit Diameter Selection in Coronary Bypass Grafting Using Saphenous Vein

AU - Szpytma, Malgorzata (Maggie)

AU - Baker, Robert A.

AU - Gimpel, Damian

AU - Newland, Richard F.

AU - Lance, David G.

AU - Rice, Gregory D.

AU - Crouch, Gareth

AU - Bennetts, Jayme S.

PY - 2024/6

Y1 - 2024/6

N2 - Background: Predictors of long-term saphenous vein graft (SVG) patency following coronary artery bypass grafting (CABG) include harvesting technique, degree of proximal coronary stenosis, and target vessel diameter and runoff. The objective of this study was to evaluate the association between vein graft diameter and long-term survival. Methods: Patients undergoing primary CABG (2000–2017) at Flinders Medical Centre, Adelaide, Australia, were categorised into three groups according to average SVG diameter (<3.5 mm [small], 3.5–4 mm [medium], >4 mm [large]). Survival data was obtained from the Australian Institute of Health and Welfare National Death Index. To determine the association of SVG diameter with long-term survival we used Kaplan-Meier survival analysis and Cox proportional hazard models adjusted for preoperative variables associated with survival. Results: Vein graft diameter was collected in 3,797 patients. Median follow-up time was 7.6 years (interquartile range, 3.9–11.8) with 1,377 deaths. SVG size >4 mm was associated with lower rates of adjusted survival up to 4 years postoperatively (hazard ratio 1.48; 95% confidence interval 1.05–2.1; p=0.026). Conclusions: Vein graft diameter >4mm was found to be associated with lower rates of survival following CABG.

AB - Background: Predictors of long-term saphenous vein graft (SVG) patency following coronary artery bypass grafting (CABG) include harvesting technique, degree of proximal coronary stenosis, and target vessel diameter and runoff. The objective of this study was to evaluate the association between vein graft diameter and long-term survival. Methods: Patients undergoing primary CABG (2000–2017) at Flinders Medical Centre, Adelaide, Australia, were categorised into three groups according to average SVG diameter (<3.5 mm [small], 3.5–4 mm [medium], >4 mm [large]). Survival data was obtained from the Australian Institute of Health and Welfare National Death Index. To determine the association of SVG diameter with long-term survival we used Kaplan-Meier survival analysis and Cox proportional hazard models adjusted for preoperative variables associated with survival. Results: Vein graft diameter was collected in 3,797 patients. Median follow-up time was 7.6 years (interquartile range, 3.9–11.8) with 1,377 deaths. SVG size >4 mm was associated with lower rates of adjusted survival up to 4 years postoperatively (hazard ratio 1.48; 95% confidence interval 1.05–2.1; p=0.026). Conclusions: Vein graft diameter >4mm was found to be associated with lower rates of survival following CABG.

KW - Bypass

KW - Conduit

KW - Coronary

KW - Diameter

KW - Saphenous vein

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U2 - 10.1016/j.hlc.2024.01.035

DO - 10.1016/j.hlc.2024.01.035

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AN - SCOPUS:85187346863

SN - 1443-9506

VL - 33

SP - 898

EP - 907

JO - Heart Lung and Circulation

JF - Heart Lung and Circulation

IS - 6

ER -

Optimal Conduit Diameter Selection in Coronary Bypass Grafting Using Saphenous Vein

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