Pancreatic insufficiency after gastrectomy: an underdiagnosed condition?

As survival rates post-gastrectomy improve, there is increased focus on postoperative outcomes and quality of life. Exocrine pancreatic insufficiency has emerged as a leading cause of gastrointestinal symptoms, with an incidence ranging from 47% to 100%. Pancreatic insufficiency results in fat malabsorption which in turn may cause steatorrhea, bloating, abdominal pain, and weight loss. Unfortunately, the consequences of fat malabsorption extend beyond just troublesome symptoms. Pancreatic insufficiency has been associated with cardiovascular disease, micronutrient deficiencies, and an inability to regain a healthy weight with associated frailty. This collectively contributes to higher morbidity and mortality rates in patients with untreated pancreatic insufficiency. It is therefore of paramount importance to recognize and treat pancreatic insufficiency promptly...