Parenteral versus oral iron therapy for adults and children with chronic kidney disease

This is a protocol for a Cochrane Review (Intervention). The objectives are as follows:

The objective of this systematic review is to determine the benefits and harms of IV iron supplementation compared with oral iron in patients with CKD, treated with haemodialysis, peritoneal dialysis or are not receiving dialysis. The review will examine the effects of these interventions on achieving target levels of Hb and iron parameters, in reduced doses of ESA required and on mortality, hospitalisation, cardiac function, quality of life as well as determining adverse effects of the therapies.